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AHPND Detection using Monoclonal Antibodies (mAbs)
Monoclonal antibodies (mAbs) with strong and specific immunoreactivity have been developed to improve the detection of acute hepatopancreatic necrosis disease (AHPND) in marine shrimp. This involves cloning and expressing recombinant PirA and PirB protein using a bacterial expression system and developing mAbs against those proteins. These monoclonal...
Published: 11/24/2025
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Inventor(s): Arun Dhar, Nam Hung Mai
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture > Aquaculture, Technology Classifications > Life Sciences > Diagnostics
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Isolation of Protein Biomarkers from Saliva as a Technology to Assess and Monitor Cardiac Infarction
This technology introduces a novel separation method designed to isolate small protein biomarkers directly from saliva, enabling a rapid and non-invasive diagnostic approach for cardiac infarction. The system employs a hybrid chromatographic matrix that selectively rejects large proteins while allowing smaller biomarkers to interact with affinity sites...
Published: 11/24/2025
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Inventor(s): Roberto Guzman, David Mier-Salazar, Christopher Rodriguez
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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Real-Time Hemoglobin-Based Blood Loss Estimation System Using Disposable Reagent Cartridges
This invention relates to a novel, real-time blood loss quantification device for use in surgical and obstetric settings. This system estimates blood volume absorbed by surgical gauze or sponges by extracting hemoglobin into a fixed-volume reagent, then quantifying absorbance using optical detection methods. This solution improves accuracy over gravimetric...
Published: 10/20/2025
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Inventor(s): Ravi Goyal
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Blood & Lymphatic Disease, Technology Classifications > Healthcare Portfolios > Emergency Medicine, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology
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Secretory Acid Sphingomyelinase Activity as a Diagnostic Marker in Colorectal Cancer
This invention utilizes the activity of secretory acid sphingomyelinase (S-SMase) in patient serum as a biomarker for the early or enhanced detection of colorectal neoplasia, including colorectal cancer (CRC).
Background:
Colorectal cancer (CRC) is one of the most common cancers worldwide, ranking third in incidence and second in cancer-related deaths...
Published: 9/22/2025
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Inventor(s): Ashley Snider, Nathan Ellis, Justin Snider, Peter Lance
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Diagnostics
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Lipid-Based Diagnostic for Minimally-Invasive Screening and Early Detection of Gynecologic Cancer
This invention is a non-invasive diagnostic for the screening and early detection of gynecologic cancers, including endometrial, cervical, and ovarian cancer, based on a lipid panel. It analyzes cervicovaginal lavages for key biomarkers that could ultimately be used a screening technology as a part of a well-woman exam to assess the risk of gynecologic...
Published: 9/22/2025
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Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
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Offline Eye Gaze-Based Visual Field Testing System
This technology introduces a portable and affordable way to perform visual field assessment using only a standard webcam and machine learning software. Unlike conventional systems that rely on costly specialized equipment and require constant supervision, this approach tracks eye movements in response to simple on-screen visual stimuli. The software...
Published: 9/15/2025
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Inventor(s): Eung Joo Lee, Paul Chong
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Ophthalmology, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Software & Information Technology > Health IT
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Biomarker for the Classification of Melanocytic Neoplasms
This invention relates to potential transcriptomic biomarkers using gene- or protein-level expression of individual or a combination of the 23 genes/proteins to accurately differentiate between low-risk, benign from high-risk, malignant melanocytic neoplasms. This approach aims to improve the accuracy of melanoma diagnosis and reduce diagnostic uncertainty.
Background:...
Published: 10/15/2025
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Inventor(s): Karen Hastings, Elizabeth Borden, Bonnie LaFleur
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
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Diagnostic for Prostate Cancer Treatment Outcomes
This technology offers a novel diagnostic tool that predicts prostate cancer treatment outcomes using a chromosomal instability signature based on nine genes. Developed through a multi-omics approach, this signature was identified in prostate epithelial cells experiencing transient centrosome loss—an event known to drive chromosomal instability...
Published: 9/8/2025
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Inventor(s): Gregory Rogers, Megha Padi, Jiawen Yang, John Ryniawec
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Urology, Technology Classifications > Life Sciences > Diagnostics
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AI-Enhanced Wearable Multi-Microphone Fetal Heart Rate Monitoring Belt with Maternal Heart Rate Differentiation
This invention is for a wearable belt encapsulating a fetal heartrate monitoring device (FHR). It employs a multi-microphone array for differentiation of maternal and feta heartbeats and utilizes data from real-time signal processing in conjunction with AI to achieve precise fetal monitoring. The device features wireless connectivity, transmitting real-time...
Published: 8/13/2025
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Inventor(s): Ravi Goyal
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices
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Lateral Flow Assay for sFlt1/PlGF Biomarker Detection in Preeclampsia Diagnosis
This technology is for a novel lateral flow strip (LFS) diagnostic assay for early diagnosis of preeclampsia in prenatal care. This point-of-care test aims to measure the soluble fms-like tyrosine kinase-1 (sFlt1) to placental growth factor (PlGF) ratio within the blood in order to determine preeclampsia risks in a timely manner. A mobile app assists...
Published: 8/13/2025
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Inventor(s): Ravi Goyal
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Urology
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