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Secretory Acid Sphingomyelinase Activity as a Diagnostic Marker in Colorectal Cancer
This invention utilizes the activity of secretory acid sphingomyelinase (S-SMase) in patient serum as a biomarker for the early or enhanced detection of colorectal neoplasia, including colorectal cancer (CRC).
Background:
Colorectal cancer (CRC) is one of the most common cancers worldwide, ranking third in incidence and second in cancer-related deaths...
Published: 9/22/2025
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Inventor(s): Ashley Snider, Nathan Ellis, Justin Snider, Peter Lance
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Diagnostics
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Lipid-Based Diagnostic for Minimally-Invasive Screening and Early Detection of Gynecologic Cancer
This invention is a non-invasive diagnostic for the screening and early detection of gynecologic cancers, including endometrial, cervical, and ovarian cancer, based on a lipid panel. It analyzes cervicovaginal lavages for key biomarkers that could ultimately be used a screening technology as a part of a well-woman exam to assess the risk of gynecologic...
Published: 9/22/2025
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Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
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Offline Eye Gaze-Based Visual Field Testing System
This technology introduces a portable and affordable way to perform visual field assessment using only a standard webcam and machine learning software. Unlike conventional systems that rely on costly specialized equipment and require constant supervision, this approach tracks eye movements in response to simple on-screen visual stimuli. The software...
Published: 9/15/2025
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Inventor(s): Eung Joo Lee, Paul Chong
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Ophthalmology, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Software & Information Technology > Health IT
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Biomarker for the Classification of Melanocytic Neoplasms
This invention relates to potential transcriptomic biomarkers using gene- or protein-level expression of individual or a combination of the 23 genes/proteins to accurately differentiate between low-risk, benign from high-risk, malignant melanocytic neoplasms. This approach aims to improve the accuracy of melanoma diagnosis and reduce diagnostic uncertainty.
Background:...
Published: 10/7/2025
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Inventor(s): Karen Hastings, Elizabeth Borden, Bonnie LaFleur
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
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Diagnostic for Prostate Cancer Treatment Outcomes
This technology offers a novel diagnostic tool that predicts prostate cancer treatment outcomes using a chromosomal instability signature based on nine genes. Developed through a multi-omics approach, this signature was identified in prostate epithelial cells experiencing transient centrosome loss—an event known to drive chromosomal instability...
Published: 9/8/2025
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Inventor(s): Gregory Rogers, Megha Padi, Jiawen Yang, John Ryniawec
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Urology, Technology Classifications > Life Sciences > Diagnostics
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AI-Enhanced Wearable Multi-Microphone Fetal Heart Rate Monitoring Belt with Maternal Heart Rate Differentiation
This invention is for a wearable belt encapsulating a fetal heartrate monitoring device (FHR). It employs a multi-microphone array for differentiation of maternal and feta heartbeats and utilizes data from real-time signal processing in conjunction with AI to achieve precise fetal monitoring. The device features wireless connectivity, transmitting real-time...
Published: 8/13/2025
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Inventor(s): Ravi Goyal
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices
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Lateral Flow Assay for sFlt1/PlGF Biomarker Detection in Preeclampsia Diagnosis
This technology is for a novel lateral flow strip (LFS) diagnostic assay for early diagnosis of preeclampsia in prenatal care. This point-of-care test aims to measure the soluble fms-like tyrosine kinase-1 (sFlt1) to placental growth factor (PlGF) ratio within the blood in order to determine preeclampsia risks in a timely manner. A mobile app assists...
Published: 8/13/2025
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Inventor(s): Ravi Goyal
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Urology
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Smart Pessaries for Uterine Prolapse
The invention is a smart pessary device designed to provide non-surgical support for pelvic organ prolapse and related conditions. It is embedded with real-time biosensors that continuously monitor vaginal pH, temperature, and hydration levels. This device also features a self-adjusting shape to ensure optimal fit and offers pelvic floor stimulation...
Published: 8/13/2025
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Inventor(s): Ravi Goyal
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Urology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices
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Δ-cps1 Mutant as a Target to Detect Coccidioides Immunity
This technology is a diagnostic platform that utilizes Flow Link Immunosorbent Assay (FLISA) and Δ-cps1, a live attenuated strain of Coccidioides posadasii, to detect if an individual (including animals) has mounted a response to coccidioidomycosis either from infection or vaccination. Δ-cps1 can be used as a stimulus to detect cellular...
Published: 10/10/2025
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Inventor(s): Daniel Powell, Lisa Shubitz, Marc Orbach, John Galgiani
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Veterinary Medicine > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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Reflex-o-Meter
The Reflex-o-Meter is a novel system designed to support clinical training, telemedicine, and future robotic healthcare applications by quantifying deep tendon reflexes (DTRs). It integrates miniature motion sensors into a standard reflex hammer and pairs them with sensors placed on a patient's limb to record and transmit reflex response data. The...
Published: 6/26/2025
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Inventor(s): Ramesh Karra, Kevin Kasper
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Health Education, Medical Training and Operations, Technology Classifications > Healthcare Portfolios > Physical Medicine & Rehabilitation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Sensors & Controls > Motion & Force
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