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This innovation is a patient-derived organoid that is used as a screening platform to study both tissues patterning and the kinase pathway dynamics in single cells across many conditions. Through this technology one is able to evaluate the patterning and homeostasis of the cells and tell when they are out of alignment. Through the use of this technology...

Published: 10/4/2023 | Inventor(s): Kelvin Pond, Curtis Thorne, Andrew Paek

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Gastroenterology Disease, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Research Tools > Cell Lines

High Dimensional Structure-Activity Relationship Approach in Cell-Based Screening for Drug Effects in Intestine

This technology is a high throughput assay utilizing 3D cell culture and multiplex antibody staining techniques to study features of the intestine under various conditions. This technology can be utilized to screen drugs for intestine-related diseases and/or examine drugs for gut toxicity. A complimentary software is then used to measure and analyze...

Published: 4/14/2023 | Inventor(s): Curtis Thorne, Elaheh Alizadeh, Kelvin Pond

Keywords(s):

Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Healthcare Portfolios > Gastroenterology Disease