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Interferometric Reflectance Confocal Microscope for Label-Free Imaging of Dynamic Sub-Cellular Activities

This invention describes the design of an interferometric reflectance confocal microscope that can achieve label-free imaging of dynamic sub-cellular activities through the use of intensity temporal fluctuation analysis in conjunction with a confocal microscopy approach and interference detection. The microscope can be used widely in biology laboratories...

Published: 6/26/2026 | Updated: 6/26/2026 | Inventor(s): Dongkyun Kang, Momoka Sugimura, Curtis Thorne

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Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry

Human Colon Polyp Derived Organoid

This innovation is a patient-derived organoid that is used as a screening platform to study both tissues patterning and the kinase pathway dynamics in single cells across many conditions. Through this technology one is able to evaluate the patterning and homeostasis of the cells and tell when they are out of alignment. Through the use of this technology...

Published: 4/17/2025 | Updated: 11/21/2022 | Inventor(s): Kelvin Pond, Curtis Thorne, Andrew Paek

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Gastroenterology Disease, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Research Tools > Cell Lines