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Organ-on-Chip Apparatus for Quantitative Study of Cellular Interaction with Ultrasound
This is an organ-to-chip device that is constructed by using thin membranes. The device allows quantitative in vitro modeling of cellular interactions by using ultrasound. The technology also has a large potential for therapeutic applications for treating different diseases. The flexibility of organ-on-chip technologies is a great tool to help speed...
Published: 11/6/2024
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Inventor(s): Jian Gu, Adam Akkad, Frederic Zenhausern
Keywords(s):
Category(s): Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences
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Container Therapeutics at Point of Care
This technology is an innovative method and system for streamlining the production of therapeutic delivery systems. Central to this innovation is the integration of various stages of production, from raw material collection to final product delivery, within a mobile infrastructure. A key embodiment involves the utilization of a container-like structure...
Published: 6/24/2024
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Inventor(s): Frederic Zenhausern
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture, Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics
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Cosmoceutical Gases-As-Drugs: Planet Atmosphere Gases Enwrapping into Soft Materials for Precise Medical Therapy
This invention enables the discovery of planetary gases and volatiles for medical gas therapy by using novel gas marbles delivery systems for tissue targeting or systemic and controlled deliveries. Gas and liquid “entrapping” into gel or foam materials have been formulated for various applications including drug delivery. This invention...
Published: 11/16/2023
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Inventor(s): Frederic Zenhausern, Joellen Russell, Michael Gordon, Justin Moser, Marta Sowinski, Ashlee Harris, Zhu Zhao, Matthew Barrett
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Anesthesiology, Technology Classifications > Life Sciences > Therapeutics
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DNA E2E: End-to-End Programmable Microfluidic Platform (PMP) for DNA Data “Write-to-Store-to-Read” with Cold Storage of DNA Data in Synthetic Fossils and Metal-Organic Scaffolds using Supercritical Fluid (SCF) Processing
The inventors have combined an error-correcting information strategy for DNA with a supercritical fluid method for drying and storing DNA. The system features an apparatus suitable for end-to-end programmable DNA storage automation using a write-to-store-to-read data cycle via a programmable microfluidic platform (PMP). The system also features a method...
Published: 4/15/2024
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Inventor(s): Frederic Zenhausern, Devasier Bennet, Tuan Vo-Dinh, Supreya Atta
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Materials > Biocompatible
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Method and System for Passive and Active Agent Delivery for Biomarker and Treatment Means
Plant-based extracellular vesicles have features leading to low immunogenicity with innate bioactive agents for targeting and/or treating specific biological effects. They can also be used as carriers with cargo drug from natural or synthetic products with higher bioavailability. The variety of plant categories also provide broad resources for lower...
Published: 11/16/2023
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Inventor(s): Frederic Zenhausern, Jerome Lacombe, Ashlee Harris, Zhu Zhao
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Drug Delivery
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Plant-Based Electrical Source
This invention is a plant-based rechargeable battery with all components produced naturally making its operations suitable for flexible, wearable, or implantable applications. It could provide novel electrical-power source directly integrated with wound healing materials for locally stimulating biological reactions with therapeutic effects. These may...
Published: 11/16/2023
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Inventor(s): Frederic Zenhausern
Keywords(s):
Category(s): Technology Classifications > Materials > Biomaterials, Technology Classifications > Energy, Cleantech & Environmental > Energy Collection, Storage & Battery, Technology Classifications > Medical Devices
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Apparatus for Active Tissue Scaffold Stretching in Cell Culture Conditions
This invention is a means to apply controlled dynamic forces on a macroscale tissue scaffold along a period of cell-culture conditions that can range from minutes to weeks. This apparatus uses a mechanically compliant substrate, which can be made from various materials, that supports the attached tissue scaffold. The apparatus also contains a holder...
Published: 8/5/2024
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Inventor(s): Ashlee Harris, Jerome Lacombe, Baiju Thomas, Matthew Barrett, Frederic Zenhausern, Alan Nordquist
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Simulators and Modeling Tools
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Smart Box for Health Logistics
This invention provides a smart container for storing of biological samples that have been collected at one site and that are being sent to another site for analysis. The containers provide a number of functional benefits, including the ability to preprocess the sample, with the preprocessing intimately tied to the transportation step and the particular...
Published: 11/16/2023
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Inventor(s): Brett Duane, Jian Gu, Alan Nordquist, Frederic Zenhausern, David Brenner, Mikhail Repin
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Health Education, Medical Training and Operations
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Method and System for Biological Information Pattern Storage and Readout
This invention is a biological information pattern (BIP) array to encode digital information into a biomolecular medium, like DNA, to store a high density of data. It also includes a label-free readout system to retrieve said information.
Background:
With a growing need for a tremendous amount of data storage there is a new demand for the use of synthetic...
Published: 11/16/2023
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Inventor(s): Frederic Zenhausern, Cedric Hurth
Keywords(s):
Category(s): Technology Classifications > Life Sciences
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Integrated Device for Self-Collecting and Automated Pre-Processing of Biological Fluids for Multiple Analyses
This invention is an integrated device where blood is collected from a skin prick and automatically transferred to prepared tubes containing reagent. The sample tubes come prepared with a specific reagent so pre-processing begins immediately and continues during transportation to the laboratory. The device incorporates several steps of biological fluid...
Published: 11/16/2023
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Inventor(s): Frederic Zenhausern, Jian Gu, Alan Nordquist
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Emergency Medicine, Technology Classifications > Medical Devices > Diagnostic
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