SAMURI-Self-Administered Multiplex Universal Radiation Indicator

Case ID:
UA23-206
Invention:

SAMURI is an innovative point-of-care biodosimetry screening kit designed to detect and measure specific proteins and transcripts within leukocytes that serve as radiation biomarkers. The kit utilizes a vertical flow immunoassay, integrating all the necessary components for sample collection, preparation, bioassay, detection, automated data analysis, and reporting into a single point-of-care solution kit. Its primary purpose is to quickly differentiate between individuals who have been exposed to radiation and those who haven't, making it particularly useful during triage after a radiological or nuclear mass casualty event, providing results in under 30 minutes. Additionally, the platform’s flexibility enables simultaneous measurement of proteins and transcripts, making it adaptable for detecting other threats and monitoring clinical biomarkers for disease management. This versatility enhances its potential appeal to industry partners.

Background: 
Current technologies for radiation exposure detection may be time-consuming, require specialized equipment, or lack the ability to provide quick results. These limitations can impede efficient triage and delay appropriate medical interventions for exposed individuals. SAMURI offers a significant improvement over current technologies by providing a comprehensive, streamlined point-of-care testing solution that enables rapid identification of exposed individuals, facilitating prompt medical attention and triage decisions. 

Applications: 

  • Radiation exposure detection
  • Biodosimetry screening
  • Mass casualty screenings (example: radiological or nuclear screenings)
  • Biological threat detection


Advantages: 

  • Rapid results
  • Point-of-care testing
  • All-in-one testing solution
  • Diagnostic use in multiple settings
Patent Information:
Contact For More Information:
Garrett Edmunds
Licensing Manager, UAHS-TLA
The University of Arizona
gedmunds@arizona.edu
Lead Inventor(s):
Frederic Zenhausern
Jerome Lacombe
Sally Amundson
Jian Gu
Helen Turner
Igor Shuryak
Michael Price
Keywords: