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SAMURI-Self-Administered Multiplex Universal Radiation Indicator
SAMURI is an innovative point-of-care biodosimetry screening kit designed to detect and measure specific proteins and transcripts within leukocytes that serve as radiation biomarkers. The kit utilizes a vertical flow immunoassay, integrating all the necessary components for sample collection, preparation, bioassay, detection, automated data analysis,...
Published: 6/4/2025
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Inventor(s): Frederic Zenhausern, Jerome Lacombe, Sally Amundson, Jian Gu, Helen Turner, Igor Shuryak, Michael Price
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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Biological Specimen Sample Preparation Apparatus for Self-Use
This invention is an apparatus with an integrated module based on a cap/tube configuration for biological specimen self-collection. A biofluidic sample, such as blood, is collected and inserted in the sample container of the sample prep module (SPM). Once inserted, the whole blood is dispensed in the chamber for a protein-based biomarker assay where...
Published: 6/4/2025
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Inventor(s): Frederic Zenhausern, James Helton, Jerome Lacombe, Jianing Yang
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Medical Devices
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Method and System for Passive and Active Agent Delivery for Biomarker and Treatment Means
Plant-based extracellular vesicles have features leading to low immunogenicity with innate bioactive agents for targeting and/or treating specific biological effects. They can also be used as carriers with cargo drug from natural or synthetic products with higher bioavailability. The variety of plant categories also provide broad resources for lower...
Published: 11/16/2023
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Inventor(s): Frederic Zenhausern, Jerome Lacombe, Ashlee Harris, Zhu Zhao
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Drug Delivery
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Apparatus for Active Tissue Scaffold Stretching in Cell Culture Conditions
This invention is a means to apply controlled dynamic forces on a macroscale tissue scaffold along a period of cell-culture conditions that can range from minutes to weeks. This apparatus uses a mechanically compliant substrate, which can be made from various materials, that supports the attached tissue scaffold. The apparatus also contains a holder...
Published: 8/5/2024
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Inventor(s): Ashlee Harris, Jerome Lacombe, Baiju Thomas, Matthew Barrett, Frederic Zenhausern, Alan Nordquist
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Simulators and Modeling Tools
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Methods For Building A Self-Contained Responsive Biological System
This technology is a new organ modeling system that utilizes plant leaves to study cancer mechanism and drug interactions. It focuses on the optimized scaffolding of decellularized plant tissues seeded with mammalian cells. The model is ideal for producing a 3D vascularized biological system that can be dynamically controlled through changes in perfusion...
Published: 11/16/2023
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Inventor(s): Jerome Lacombe, Ashlee Harris, Ryan Zenhausern, Frederic Zenhausern
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Microfluidics, Technology Classifications > Research Tools
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