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Metabolic Screening Methods for Endometrial Cancer
Researchers at the University of Arizona employed cervicovaginal lavage sampling and a global untargeted metabolomic approach to identify potential biomarkers for endometrial cancer. The study's novel approach involved linking cervicovaginal metabolite levels to crucial tumor characteristics such as size, histological grade, and myometrial invasion,...
Published: 3/1/2024
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Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
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Phenyllactic Acid: Antimicrobial Activity against Vaginal Microbiota and Cytotoxic Properties on Human Cervical Epithelial Cells
Researchers at the University of Arizona investigated the antimicrobial properties of Phenyllactic Acid (PLA) derivatives against both commensal and Bacterial vaginosis (BV)-associated bacteria, as well as their cytotoxic effects on human cervical epithelial cells. PLA is a broad-spectrum antimicrobial compound produced by vaginal Lactobacillus species;...
Published: 1/16/2024
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Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski, Abhijit Date, Phoebe Crossley
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Infectious Diseases
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Methods for Guiding Treatments of Vulvovaginal Symptoms and Female Sexual Dysfunction
Multi-omics analysis of cervicovaginal samples has led to the identification of a specific immune mediators, metabolites, and bacteria that are associated with vulvovaginal and sexual health symptoms. These biomarkers hold the potential to be utilized in a non-invasive test that guides the treatment of vulvovaginal symptoms and female sexual dysfunction...
Published: 1/16/2024
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Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Therapeutics
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A Steerable, Optically Guided System for Detection of Ureteral Injury and Ureteral Catheterization
This technology is a therapeutic and diagnostic one-time-use device to place a ureteral catheter or stent without fluoroscopic guidance. Enhancements to the device may allow detection of injury to the ureter via Optical Coherence Tomography (OCT) and treatment of nephrolithiasis via laser lithotripsy. This small-diameter ureteral catheter or stent comprises...
Published: 1/22/2024
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Inventor(s): John Heusinkveld, Jennifer Barton, Dominique Galvez, Andrew Rocha, William Drake
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Healthcare Portfolios > Urology, Technology Classifications > Healthcare Portfolios > Women's Health
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Diagnostic for Non-Invasive Screening and Early Detection of Adenomyosis
This technology is a non-invasive diagnostic for the screening and detection of adenomyosis. This could be used for women who are suffering with symptoms of chronic pelvic pain and adenomyosis for diagnosis without an invasive hysterectomy. In preliminary studies, there have been high acceptance of a particular sampling, that can provide information...
Published: 2/16/2024
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Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Women's Health
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Diagnostic for Screening and/or Predicting Women "at risk" for the Development and Progression Endometrial Cancer
This invention describes a novel method to use metabolic markers in samples obtained from cervicovaginal lavage (CVL) and machine-learning algorithms to detect patients “at risk” for endometrial cancer (EMC).
Background:
Endometrial cancer (EMC) is the most common gynecological cancer. The American Cancer Society estimates that in 2021...
Published: 11/16/2023
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Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Healthcare Portfolios > Women's Health
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Diagnostic for Monitoring Response to Immunotherapies for Gynecologic Cancer
This invention is a collection of immunological checkpoint proteins and physiological markers to diagnose and potentially monitor treatments for cervical cancer. This biomarker panel would be taken using the cervicovaginal lavage method, which is a less invasive than other sampling method for cervical cancer. This diagnostic test could be used not only...
Published: 2/16/2024
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Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
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Diagnostic Tool For Estrogen Receptor Positive Breast Cancer Patient Stratification
This technology is a set of biomarkers to stratify estrogen receptor positive breast cancer patients to see if they should receive anti-estrogen therapy or not.
Background:
Breast cancer, the second most common cancer among American women, will effect of 330,000 new patients this year. The most commonly diagnosed breast tumors are estrogen receptor...
Published: 4/3/2023
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Inventor(s): Ghassan Mouneimne, Marco Padilla-Rodriguez
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Diagnostics
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Obstetrics Critical Care VR Training Volume 1, Episodes 1 & 2
This invention is a series of educational videos created to be viewed with virtual reality (VR) technologies to provide an experiential learning experience specific to crisis management for obstetric care providers.
Background:
VR technology is poised to be a disruptive technology that will change the education of health care. VR technology can...
Published: 6/26/2023
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Inventor(s): Michael Foley
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Imaging & Optics, Technology Classifications > Software & Information Technology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Software & Information Technology > Education & Training, Technology Classifications > Software & Information Technology > Health IT
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