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ARTHUR (Autonomous Remote Telesurgery for Healing in Underserved Regions)

This invention introduces the ability to perform laser-based wound debridement remotely using computer vision and AI. The invention pioneers the remote execution of such procedures, offering a glimpse into a future where medical interventions can be conducted from a distance, potentially revolutionizing healthcare accessibility and efficiency. This...

Published: 4/8/2024 | Inventor(s): Geoffrey Gurtner

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity, Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Mobile Application, Technology Classifications > Software & Information Technology > Human Machine Interface

Transplantable Murine Cutaneous Squamous Cell Carcinoma Cell Lines

This innovation involves the creation of novel cell lines for studying cutaneous squamous cell carcinoma (cSCC) in mice. These cell lines, derived from UV-induced cSCC tumors in BALB/c mice, recapitulate the mutational signature and driver mutations found in human cSCC. Developing the cell lines from an inbred mouse strain allows for studies involving...

Published: 4/11/2024 | Inventor(s): Karen Hastings, Anngela Adams, Anne Macy

Keywords(s):

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Healthcare Portfolios > Oncology

Pharmacological Inhibition of PD-L1 as an Antagonist of Skin Damage and Cancer in response to Acute and Chronic Solar UV Exposure and Other Environmental Toxicants

This innovation is the development of a pharmacological inhibitor of PD-L1 to prevent or reduce the negative impact of acute and chronic solar UV exposure and environmental toxicants on the skin. PD-L1 is a molecule involved in immune regulation and can be upregulated in response to UV radiation and environmental toxins. However, overexpression of PD-L1...

Published: 3/6/2024 | Inventor(s): Sally Dickinson, Georg Wondrak, Clara Curiel

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Dermatology

Methods and System for Closed-Loop Ultrasound and Photoacoustic Imaging

This technology is a novel closed-loop volumetric ultrasound and photoacoustic imaging and spectroscopy method that is operator-independent. The technology can be integrated with existing hardware systems, and it offers the flexibility to scale from standard clinical ultrasound to high-frequency preclinical imaging for visualizing structures at different...

Published: 1/16/2024 | Inventor(s): Russell Witte, Eric Reichel, Clara Curiel, Christopher Salinas, Delaney Stratton

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Dermatology

Sugar-Based Low Molecular Weight Hydrogels from Alkyl Glycolipids

University of Arizona researchers have created sugar-based low molecular weight hydrogels that spontaneously self-assemble through weak, noncovalent intermolecular interactions. These gels are thixotropic, biocompatible, and biodegradable. Despite being held together through non-covalent interactions, these hydrogels exhibit greater mechanical strength...

Published: 3/12/2024 | Inventor(s): Jeanne Pemberton, Laurel Kegel, Yu-Cheng Wang

Keywords(s):

Photochemically Stable, Non-Leaching, Bridged Polysilsesquioxane Based Sunscreens

This technology is a non-toxic, long-lasting sun protection based on nanoparticles of bridged polysilsesquioxanes. Background: UV radiation (100 – 400 nm) represents ~10% of electromagnetic radiation (sunlight) that reaches the Earth's surface, and can be separated into three main types: UVC (100 – 290 nm), which has the shortest...

Published: 4/3/2023 | Inventor(s): Douglas Loy, Stephanie Tolbert

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Materials > Nanomaterials, Technology Classifications > Materials > Polymers

Sunscreens Based on Phenolic-Formaldehyde Particles

Sun-protective polymeric particles using a micro emulsion polymerization by nucleation approach have been developed by researchers at the University of Arizona. The resulting resorcinol-formaldehyde is red to brown in color with strong absorption of UVA and UVB radiation, making it an ideal material for sunscreen. Resorcinol-formaldehyde has been widely...

Published: 2/1/2024 | Inventor(s): Douglas Loy, Robb Bagge, Nanayakkarawasan Pallage Nanayakkara

Keywords(s): nano-particles

Category(s): Technology Classifications > Healthcare Portfolios > Dermatology

Sunscreens Prepared from Polydopamine and Poly (dopamine-co-cafeic acid)

This invention is synthetic eumelanin particles prepared by polymerization of dopamine that can be dispersed in water, glycerol or oil. Background: Sunscreen products in the market today are typically made of potentially harmful chemicals, including avobenzone, which releases cancer-causing free radicals, and oxybenzone, which has estrogenic properties...

Published: 2/1/2024 | Inventor(s): Douglas Loy, Robb Bagge, Nanayakkarawasan Pallage Nanayakkara

Keywords(s): nano-particles

Category(s): Technology Classifications > Healthcare Portfolios > Dermatology

New Sunscreens Based on Particles Prepared from Higher Aldehydes and Phenols

This invention consists of particles that can be used as sunscreens prepared by the copolymerization of phenols with aromatic and conjugated aldehydes like cinnamaldehyde or benzaldehyde. These particles made of bio-based materials can be dispersed in liquid and function as thermosets for sun-blocking purposes. Background: Sunscreen products in the...

Published: 2/1/2024 | Inventor(s): Douglas Loy, Robb Bagge, Nanayakkarawasan Pallage Nanayakkara

Keywords(s): nanoparticles

Category(s): Technology Classifications > Healthcare Portfolios > Dermatology

Targeted Therapy for Itch

TMEM184B is a relatively uncharacterized 7-pass transmembrane protein that is a member of the Transporter-Opsin-GPCR (TOG) superfamily of proteins. It was discovered that over-expression of TMEM184B caused a reduction in scratching in response to interleukin-31 (Il-31) exposure. This was surprising given previous studies had shown that knock-out of...

Published: 3/12/2024 | Inventor(s): Martha Bhattacharya, Tally Largent-Milnes

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Life Sciences > Therapeutics

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