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Targeted Therapy for Itch
TMEM184B is a relatively uncharacterized 7-pass transmembrane protein that is a member of the Transporter-Opsin-GPCR (TOG) superfamily of proteins. It was discovered that over-expression of TMEM184B caused a reduction in scratching in response to interleukin-31 (Il-31) exposure. This was surprising given previous studies had shown that knock-out of...
Published: 3/12/2024   |   Inventor(s): Martha Bhattacharya, Tally Largent-Milnes
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Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Life Sciences > Therapeutics