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Isolation and Separation of Angiotensin I and II from Human Serum Using a New Chromatographic Matrix that Excludes High Molecular Weight Proteins
This innovation introduces a novel chromatographic matrix that effectively isolates and separates angiotensin I and II, key biomarkers involved in blood pressure regulation, from human serum. The system uses a hybrid combination matrix that selectively removes small molecular weight polypeptides while excluding large serum proteins. By integrating chelating...
Published: 1/6/2026
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Inventor(s): Roberto Guzman, David Mier-Salazar, Daniel Alejandro Diaz
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Blood & Lymphatic Disease, Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic
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Analytical Technology for the Isolation of 3-Nitrotyrosine as a Biomarker from Urine to Assess Depression and Acute Kidney Injury
This invention uses a novel separation technique to isolate specific biomarkers from urine, as a measure to detect and monitor depression and acute kidney injury (AKI). The system employs a hybrid chromatographic matrix that rejects biomolecules of specific sizes and allows only the desired small compounds, such as 3-nitrotyrosine (which has been linked...
Published: 1/6/2026
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Inventor(s): Roberto Guzman, David Mier-Salazar
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Nephrology/Renal, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic
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SAGE: A Low-Cost, High-Throughput Disease Agnostic Microfluidic Discovery Engine
This technology relates to a low-cost, high throughput microfluidic platform device which can help identify therapeutic compounds from a known agent, such as tuberculosis. Through a three-chip process, the invention can encapsulate, cultivate, screen and sort bacteria from a host of environmental microbes for bioactive natural products. The platform...
Published: 12/8/2025
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Inventor(s): Christopher Cartmell, John Streicher
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Research Tools
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Isolation of Protein Biomarkers from Saliva as a Technology to Assess and Monitor Cardiac Infarction
This technology introduces a novel separation method designed to isolate small protein biomarkers directly from saliva, enabling a rapid and non-invasive diagnostic approach for cardiac infarction. The system employs a hybrid chromatographic matrix that selectively rejects large proteins while allowing smaller biomarkers to interact with affinity sites...
Published: 11/24/2025
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Inventor(s): Roberto Guzman, David Mier-Salazar, Christopher Rodriguez
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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Real-Time Hemoglobin-Based Blood Loss Estimation System Using Disposable Reagent Cartridges
This invention relates to a novel, real-time blood loss quantification device for use in surgical and obstetric settings. This system estimates blood volume absorbed by surgical gauze or sponges by extracting hemoglobin into a fixed-volume reagent, then quantifying absorbance using optical detection methods. This solution improves accuracy over gravimetric...
Published: 10/20/2025
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Inventor(s): Ravi Goyal
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Blood & Lymphatic Disease, Technology Classifications > Healthcare Portfolios > Emergency Medicine, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology
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Spectrometer-Free Biosensing Using Photonic Diffractive Computing for Direct Optical Readout
This invention introduces a photonic diffractive computing biosensing system that converts analyte-induced spectral changes directly into distinct spatial intensity patterns, enabling classification or concentration measurement without spectral reconstruction. An element in the system produces a resonance shift after detection, which produces a diffraction...
Published: 12/23/2025
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Inventor(s): Mohamed ElKabbash
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Sensors & Controls > Biologic
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SHIP: A Smart Non Wearable Device to Track Sleep Hygiene and Diagnose Sleep Disorders
The Sleep Hygiene Innovation Pillow (SHIP) is a non-wearable smart system that transforms a traditional pillow into a health monitoring device. SHIP uses sensors to continuously record head movement patterns during sleep, then processes that data through proprietary signal analysis and a machine learning algorithm that distinguishes between normal physiological...
Published: 9/19/2025
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Inventor(s): Sumit Agarwal, Joyce Iannotti, Pooja Rangan
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Mobile Application
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Lateral Flow Assay for sFlt1/PlGF Biomarker Detection in Preeclampsia Diagnosis
This technology is for a novel lateral flow strip (LFS) diagnostic assay for early diagnosis of preeclampsia in prenatal care. This point-of-care test aims to measure the soluble fms-like tyrosine kinase-1 (sFlt1) to placental growth factor (PlGF) ratio within the blood in order to determine preeclampsia risks in a timely manner. A mobile app assists...
Published: 8/13/2025
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Inventor(s): Ravi Goyal
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Urology
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Δ-cps1 Mutant as a Target to Detect Coccidioides Immunity
This technology is a diagnostic platform that utilizes Flow Link Immunosorbent Assay (FLISA) and Δ-cps1, a live attenuated strain of Coccidioides posadasii, to detect if an individual (including animals) has mounted a response to coccidioidomycosis either from infection or vaccination. Δ-cps1 can be used as a stimulus to detect cellular...
Published: 10/10/2025
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Inventor(s): Daniel Powell, Lisa Shubitz, Marc Orbach, John Galgiani
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Veterinary Medicine > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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Water Immersion Multi-Slit Portable In Vivo Confocal Ophthalmoscope
This technology is a low-cost, portable, scan-less in vivo confocal ophthalmoscope (PICO) that uses a water-immersion objective lens in combination with a multi-slit illumination and detection system. It enables high-resolution, non-invasive imaging of the anterior segment and external structures of the eye at the cellular and subcellular level. The...
Published: 7/22/2025
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Inventor(s): Dongkyun Kang, Kenneth Marcelino, Momoka Sugimura, Jaya Chidambaram
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Displays, Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry, Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Imaging & Optics > Ophthalmology, Technology Classifications > Healthcare Portfolios > Ophthalmology, Technology Classifications > Medical Devices > Diagnostic
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