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Hadamard Transform-Charge Detection-Mass Spectrometry
This technology uses a multiplexing approach to online size exclusion chromatography (SEC) coupled with Orbitrap CD-MS. A microcontroller is used to deliver pulsed injections from a large sample loop onto a SEC for online CD-MS analysis. The method produces a series of peaks spaced according to the pseudo-random injection sequence, which are demultiplexed...
Published: 3/29/2024
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Inventor(s): Michael Marty, James Sanders
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Engineering & Physical Sciences, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry
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Compressing Ion-Beam Shutter
The compressing ion-beam ion shutter developed at The University of Arizona is composed of a series of electrically charged screens. By varying the relative voltages on the screens, the flow of ions into the detector chamber is blocked or opened. When the shutter is first opened, ions accumulate between the screens. When the shutter voltage is changed,...
Published: 3/12/2024
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Inventor(s): Roger Sperline
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry
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Surface-Modified Electrospray Needles for Mass Spectrometry
With this invention, electrospray needles used in mass spectrometry are coated to prevent sticking and clogging of analytes, resulting in improved mass detection sensitivity and consistency of analysis. The coating comprises an organic material covalently bonded to an interior surface of the electrospray needle. The coating is electrically non-conductive...
Published: 3/12/2024
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Inventor(s): Michael Marty, Craig Aspinwall, Marius Kostelic, Chih-Chieh Hsieh
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Microfluidics, Technology Classifications > Materials > Coatings
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Deconvolution of Charge Detection-Mass Spectrometry Data
This mass spectrometry analysis software and method extends the UniDec Bayesian deconvolution algorithm for application to two-dimensional charge detection-mass data. A 2D plot of m/z versus charge is created from raw data. Smoothing and background subtraction may be used, and deconvolution is applied to remove uncertainty in the charge and the m/z...
Published: 3/12/2024
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Inventor(s): Michael Marty, Marius Kostelic
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry
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Micro Faraday-Element Array Detector for Ion Mobility Spectroscopy
The novel ion mobility spectrometry (IMS) includes a drift tube having a collecting surface covering a collecting area at one end of the tube. The surface comprises a plurality of closely spaced conductive elements on a non-conductive substrate, each conductive element being electrically insulated from each other element. A plurality of capacitive transimpedance...
Published: 3/12/2024
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Inventor(s): M Denton, Roger Sperline, Christopher Gresham, Phillip Rodacy
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry
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Differential Transimpedance Amplifier Circuit for Correlated Differential Amplification
Researchers at the University of Arizona have created a differential transimpedance amplifier circuit for correlated differential amplification. The amplifier circuit increases electronic signal-to-noise ratio in charge detection circuits designed for the detection of very small quantities of electrical charge and/or very weak electromagnetic waves....
Published: 3/12/2024
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Inventor(s): M Denton, Roger Sperline, Christopher Gresham
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry
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