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Deep Learning Algorithm for Detection of Cortical Arousal During Sleep
This invention is an end-to-end deep learning algorithm to detect cortical arousals during sleep using a one-night single lead electrocardiogram (ECG) signal. It is used to accurately detect arousal in home sleep tests, by reducing the false negative rate. The model combines both convolutional neural networks (CNN) and recurrent neural networks (RNN).
Background:
Sleep...
Published: 3/28/2024
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Inventor(s): Ao Li, Siteng Chen, Stuart Quan, Linda Powers, Janet Roveda
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Software & Information Technology > Health IT
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Tributyrin to Entain Human Circadian Rhythms and Improve Sleep in Individuals with Medical Disorders that can Increase Gut Permeability or Elevated Levels of Systemic Inflammation
This documents a new method of treatment for sleep improvements. Poor sleep is likely manifested by an underlying irregular circadian rhythm sleep disorder. A patient with a history of leaky gut syndrome and poor sleep took a commercially available oral short-chain fatty acid supplement, tributyrin, and documented improved sleep. This suggests a relationship...
Published: 1/10/2024
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Inventor(s): Sairam Parthasarathy
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Healthcare Portfolios > Sleep Disorders
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Green-Enhancer Glasses
This invention is an optical filter which blocks out blue light and only allows green to pass through, increasing the relative amount of green light that passes through. This filter can be used on prescription and non-prescription glasses, as well as on coverings for lamps and light bulbs. Green light in the morning can rehabilitate the circadian system...
Published: 6/23/2023
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Inventor(s): Fabian Fernandez, Michael Grandner, Stanley Pau, Brooke Mason
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Healthcare Portfolios > Sleep Disorders
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Melanopsin Blocker
This invention describes an optical filter that can be used in the production of glasses that block wavelengths of light harmful to circadian rhythms and sleep.
Background:
The great importance of maintaining a healthy circadian rhythm and getting good sleep continues to be firmly supported by researchers, and more healthy sleep is known to produce...
Published: 3/12/2024
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Inventor(s): Fabian Fernandez, Michael Grandner, Stanley Pau, Brooke Alexander
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Imaging & Optics > Lens & System Design
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Circadian Rhythm Restoring Blue Blockers
This technology is for glasses that are to be worn at night to block harmful blue light from artificial light sources. Specifically, these glasses block wavelengths associated with circadian-active light, which causes melatonin suppression. This intervention restores the endogenous rhythms of users and leads to better sleep patterns.
Background:
With...
Published: 1/31/2024
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Inventor(s): Michael Grandner, Brooke Mason, Fabian Fernandez, Stanley Pau
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Life Sciences
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Blue-Enhancer Glasses
Because of the huge increase in the amount of blue light consumed by the average individual due to myriad factors including society’s dependence on phones, tablets, and computers, blue light blocking glasses are becoming commonplace. Not only do blue light suppressing glasses decrease some of the stress on an individuals’ eyes, but the decrease...
Published: 1/31/2024
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Inventor(s): Michael Grandner, Brooke Mason, Fabian Fernandez, Stanley Pau
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Imaging & Optics > Lens & System Design
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Kappa Opioid Receptor Antagonists for Sleep Disorders
Researchers at UArizona have discovered that kappa opioid receptors influence sleep in mice struggling with chronic pain. In particular they found that a kappa opioid receptor antagonist could be beneficial for improvement of sleep related to pain conditions, as well as other conditions where increased kappa opioid receptor signaling has been observed....
Published: 4/3/2023
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Inventor(s): Frank Porreca, Hisakatsu Ito, Edita Navratilova
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Life Sciences > Therapeutics
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Circadian Responses to Light-Flash Exposure: Conceptualization and Data Guiding Future Directions
Though perhaps not often thought of first, the circadian system in the human body is essential to important daily and cyclical bodily functions including: hormone release, temperature control, eating habits, mood, sleep, etc. Those circadian responses in the human body are primarily triggered by light exposure. There is a body of research surrounding...
Published: 4/3/2023
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Inventor(s): Fabian Fernandez, Jamie Zeitzer, Horace Heller
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Life Sciences > Diagnostics
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Evaluating Hotels to Optimize Guest Sleep
Excluding the exigent circumstances of 2020, the United States has approximately 4.9 million hotel rooms and, at any given time, approximately 3 million of those are occupied. The increased ability of people to travel all over the United States and the world is a trend that continues to rise. While hotels provide a number of amenities for guest comfort...
Published: 4/3/2023
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Inventor(s): Michael Grandner, Rebecca Robbins
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Medical Devices > Diagnostic
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Assessment of Sleep Environment (ASE)
This invention is a 13-item questionnaire that assesses the degree to which an individual's environment impacts on their sleep. It measures light/dark, noise/quiet, smell, humidity, sleeping surface, safety, and other factors.
Background:
In spite of the relatively short history of sleep and sleep disorder research, significant progress has been...
Published: 4/3/2023
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Inventor(s): Michael Grandner
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Life Sciences > Diagnostics
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