|
Isolation and Separation of Angiotensin I and II from Human Serum Using a New Chromatographic Matrix that Excludes High Molecular Weight Proteins
This innovation introduces a novel chromatographic matrix that effectively isolates and separates angiotensin I and II, key biomarkers involved in blood pressure regulation, from human serum. The system uses a hybrid combination matrix that selectively removes small molecular weight polypeptides while excluding large serum proteins. By integrating chelating...
Published: 1/6/2026
|
Inventor(s): Roberto Guzman, David Mier-Salazar, Daniel Alejandro Diaz
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Blood & Lymphatic Disease, Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic
|
|
Analytical Technology for the Isolation of 3-Nitrotyrosine as a Biomarker from Urine to Assess Depression and Acute Kidney Injury
This invention uses a novel separation technique to isolate specific biomarkers from urine, as a measure to detect and monitor depression and acute kidney injury (AKI). The system employs a hybrid chromatographic matrix that rejects biomolecules of specific sizes and allows only the desired small compounds, such as 3-nitrotyrosine (which has been linked...
Published: 1/6/2026
|
Inventor(s): Roberto Guzman, David Mier-Salazar
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Nephrology/Renal, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic
|
|
Isolation of Protein Biomarkers from Saliva as a Technology to Assess and Monitor Cardiac Infarction
This technology introduces a novel separation method designed to isolate small protein biomarkers directly from saliva, enabling a rapid and non-invasive diagnostic approach for cardiac infarction. The system employs a hybrid chromatographic matrix that selectively rejects large proteins while allowing smaller biomarkers to interact with affinity sites...
Published: 11/24/2025
|
Inventor(s): Roberto Guzman, David Mier-Salazar, Christopher Rodriguez
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
|
|
Lipid-Based Diagnostic for Minimally-Invasive Screening and Early Detection of Gynecologic Cancer
This invention is a non-invasive diagnostic for the screening and early detection of gynecologic cancers, including endometrial, cervical, and ovarian cancer, based on a lipid panel. It analyzes cervicovaginal lavages for key biomarkers that could ultimately be used a screening technology as a part of a well-woman exam to assess the risk of gynecologic...
Published: 9/22/2025
|
Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
|
|
Biomarker for the Classification of Melanocytic Neoplasms
This invention relates to potential transcriptomic biomarkers using gene- or protein-level expression of individual or a combination of the 23 genes/proteins to accurately differentiate between low-risk, benign from high-risk, malignant melanocytic neoplasms. This approach aims to improve the accuracy of melanoma diagnosis and reduce diagnostic uncertainty.
Background:...
Published: 10/15/2025
|
Inventor(s): Karen Hastings, Elizabeth Borden, Bonnie LaFleur
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
|
|
Predictive mRNA Biomarker for Progressive Coccidioidomycosis When Infected
This invention introduces a blood-based diagnostic test to assess coccidioidomycosis progression risk. The test is broken down into three overall steps: 1) blood collection, 2) ex vivo stimulation, and 3) mRNA quantification. This technology identified a predictive a gene set/biomarkers for coccidioidomycosis that was independently validated across...
Published: 7/22/2025
|
Inventor(s): John Galgiani, Yves Lussier
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools
|
|
Endoglin Antibody
This technology is the use of endoglin-specific antibodies to enhance the detection process of certain cancers, offering a more precise and reliable approach to identifying cancer-related variants of endoglin. Directed toward an antibody to a mutated endoglin protein, this antibody provides methods and compositions for detecting splice variants of the...
Published: 5/30/2025
|
Inventor(s): Nam Lee
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Antibodies
|
|
Factor XII(a) is a Biotarget for Treatment of Dilated Cardiomyopathy and Heart Failure
Researchers at the University of Arizona have identified a novel, previously unrecognized harmful role of coagulation factor, Factor XII (FXII) and/or activated coagulation factor XIIa (fXII(a)) in modulating the progression of dilated cardiomyopathy and heart failure development. They have proposed fXII(a) as a new biotarget to treat dilated cardiomyopathy...
Published: 12/4/2024
|
Inventor(s): Guy Reed, Inna Gladysheva, Ryan Sullivan
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Heart and Vascular
|
|
Colorectal Cancer Prognostic/Prediction
This technology provides a gene score system to assess the effectiveness of antifibrotic treatments on colorectal cancer (CRC). By comparing gene expressions from colorectal cancer cells under two different types of mechanical conditioning, this system identifies specific gene signatures that correlate with an increased risk of metastasis and lower...
Published: 4/1/2025
|
Inventor(s): Ghassan Mouneimne
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools
|
|
Myelin Breakdown Products as Plasma Biomarkers of Therapeutic Efficacy in the Acute Phase after Stroke
This invention pertains to the use of myelin breakdown products, such as lipids indicative of brain lipid catabolism, as plasma biomarkers for the diagnosis and prognosis of ischemic stroke (IS). Researchers discovered an acute signature of brain lipid catabolism in the plasma 24 hours after a stroke in mouse model research. Notably, a substantial proportion...
Published: 8/12/2024
|
Inventor(s): Kristian Doyle, Danielle Becktel
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Biomarkers
|
