Invention:
This invention is a non-invasive diagnostic for the screening and early detection of gynecologic cancers, including endometrial, cervical, and ovarian cancer, based on a lipid panel. It analyzes cervicovaginal lavages for key biomarkers that could ultimately be used a screening technology as a part of a well-woman exam to assess the risk of gynecologic cancers.
Background:
Cervical cancer is the fourth most common cancer in women, globally. Endometrial cancer is the sixth most common cancer in women, globally. Current first-line definitive diagnostic methods for endometrial cancer involve biopsy pipelles or dilation and curettage, both of which are invasive. Less invasive approaches may be unsuitable for some women or may lack adequate sensitivity and specificity. A diagnostic method that overcomes these limitations—such as this invention—is needed.
Applications:
- Gynecologic cancer diagnostic
- Lipid biomarkers
- Well-woman exams
- Predictive oncology
- Personalized cancer treatment
Advantages:
- Minimally invasive method of screening and diagnosis
- Potentially increased sensitivity and specificity
- Enables early detection of gynecologic cancers, including endometrial, cervical, and ovarian cancers
