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Δ-cps1 Mutant as a Target to Detect Coccidioides Immunity
This technology is a diagnostic platform that utilizes Flow Link Immunosorbent Assay (FLISA) and Δ-cps1, a live attenuated strain of Coccidioides posadasii, to detect if an individual (including animals) has mounted a response to coccidioidomycosis either from infection or vaccination. Δ-cps1 can be used as a stimulus to detect cellular...
Published: 8/11/2025
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Inventor(s): Daniel Powell, Lisa Shubitz, Marc Orbach, John Galgiani
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Veterinary Medicine > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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Predictive mRNA Biomarker for Progressive Coccidioidomycosis When Infected
This invention introduces a blood-based diagnostic test to assess coccidioidomycosis progression risk. The test is broken down into three overall steps: 1) blood collection, 2) ex vivo stimulation, and 3) mRNA quantification. This technology identified a predictive a gene set/biomarkers for coccidioidomycosis that was independently validated across...
Published: 7/22/2025
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Inventor(s): John Galgiani, Yves Lussier
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools
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Antibody Test for Coccidioidomycosis
This invention is a novel diagnostic test for coccidioidomycosis, also known as valley fever.
Background:
Valley fever (coccidioidomycosis) is a fungal disease that is a common cause for pneumonia due to spores that are swept through the air. The fungal infection can be identified in microscopic detection of specific cells within bodily fluids....
Published: 6/6/2024
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Inventor(s): John Galgiani, Michael Johnson
Keywords(s):
Category(s): Technology Classifications > Veterinary Medicine > Diagnostics, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
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Domain of a Protein Antigen from Coccidioides immitis which Induces Protection Against Coccidoidal Infection
Researchers at the University of Arizona have determined the precise conformation required to confer resistance to C. immitis or Valley Fever, which is endemic to Southwestern United States, Mexico, and other Latin American countries. They have identified a subunit of C. immitis antigen that would both prevent coccidioidomycosis and optimize the vaccine...
Published: 4/3/2023
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Inventor(s): John Galgiani, Kris Orsborn, Tao Peng, Lisa Shubitz
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Veterinary Medicine, Technology Classifications > Veterinary Medicine > Therapeutics & Vaccines, Technology Classifications > Life Sciences > Therapeutics
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