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Δ-cps1 Mutant as a Target to Detect Coccidioides Immunity

This technology is a diagnostic platform that utilizes Flow Link Immunosorbent Assay (FLISA) and Δ-cps1, a live attenuated strain of Coccidioides posadasii, to detect if an individual (including animals) has mounted a response to coccidioidomycosis either from infection or vaccination. Δ-cps1 can be used as a stimulus to detect cellular...

Published: 8/11/2025 | Inventor(s): Daniel Powell, Lisa Shubitz, Marc Orbach, John Galgiani

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Veterinary Medicine > Diagnostics, Technology Classifications > Medical Devices > Diagnostic

A Natural Mouse Model that Enables the Discovery and Characterization of Bacterial and Host Factors that Mediate Neisseria Colonization and Persistence, and Targets for Vaccines and Antimicrobials

This technology is a natural small animal model that circumvents the barriers of host restriction, often seen when studying Neisseria species. This model can be used to study host determinants controlling colonization resistance and factors involved in Neisseria-host interactions and screening therapeutics and vaccines against Neisseria. Background: Neisseria...

Published: 4/3/2023 | Inventor(s): Magdalene So, Jeffrey Frelinger, Man Cheong Ma, Daniel Powell, Katherine Rhodes, Nathan Weyand

Keywords(s):

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Healthcare Portfolios > Infectious Diseases