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Shelf-Stable Reagent for Bioconjugation and Protein Labeling
This invention is a new class of amine-reactive, water-stable, small molecules for use as probes, reagents, or bioconjugates. These molecules are lysine-reactive and conjugate quickly without the need for coupling reagents or catalysts. The molecules are simple to synthesize and purify, with high yields. These materials selectively react with lysine...
Published: 3/12/2024
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Inventor(s): John Jewett, Garrett Davis, Holly Sofka
Keywords(s):
Category(s): Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Protein, Technology Classifications > Research Tools > Reagents, Technology Classifications > Life Sciences > Diagnostics
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Monoclonal Antibodies Useful for the Detection of Cryptosporidiosis
Monoclonal antibodies have been developed that detect specific Cryptosporidium antigens. These antibodies are useful for a broad range of research and development purposes and, importantly, these reagents offer the opportunity for the development of a rapid, highly sensitive diagnostic test, capable of simultaneously detecting multiple causative agents...
Published: 4/3/2023
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Inventor(s): Michael Riggs, Deborah Schaefer
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Veterinary Medicine, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Veterinary Medicine > Diagnostics, Technology Classifications > Life Sciences > Diagnostics
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Monoclonal Antibodies to the Calpain Small Subunit
University of Arizona researchers have developed antibodies specific to the calpain small subunit. They have developed two hybridoma clones which produce antibodies specific to the 28kDa small subunit of both mu and m-calpain.
Background:
As calpains have been proposed to be proteases important in apoptotic reactions in human cells, further research...
Published: 4/3/2023
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Inventor(s): Darrel Goll
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Life Sciences > Diagnostics
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A Novel Anti-Polysaccharide Antiserum for Detection of Clostridium difficile Bacteria, and Diagnosis of Clostridium difficile Colonization in Complex Clinical Specimens
This technology is an antiserum that is highly specific for Clostridium difficile. This target is available on all clinically relevant strains of Clostridium difficile bacteria.
Background:
Clostridium difficile is a bacteria that causes serious intestinal issues. Each year there are approximately 500,000 cases of Clostridium difficile in the United...
Published: 4/3/2023
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Inventor(s): Gayatri Vedantam, Virinchipuram Viswanathan
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Antibodies
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Hybridoma Clones and Monoclonal Antibodies to ING4
This invention is directed to a monoclonal antibody that recognizes human ING4 in its native form. The invention is also directed to a hybridoma cell line that produces the monoclonal antibody, and to methods of diagnosing cancer using the antibody.
Background:
ING4 is a member of the ING tumor suppressor family and has been shown to play a role...
Published: 11/16/2023
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Inventor(s): Suwon Kim, David Azorsa
Keywords(s):
Category(s): Technology Classifications > Research Tools > Antibodies
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