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C41 Analogs
This invention relates generally to neurodegenerative diseases and conditions, such as Alzheimer’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 9/24/2024
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Inventor(s): Wei Wang, Rui Chang, Vijayan Ramachandran, Patrick Ronaldson
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Biologics
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Cosmetic Hyaluronic Acid Binding Peptides
The invention focuses on developing a novel gel technology aimed at rejuvenating aging skin by targeting hyaluronic acid (HA) receptors. These receptors, crucial for skin hydration and elasticity, decline with age, contributing to skin aging. The gel incorporates peptides designed to mimic HA receptors, enhancing their binding to HA molecules and effectively...
Published: 8/5/2024
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Inventor(s): Kyle Koss, Terrance Sereda
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Life Sciences > Biologics
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CC16-Derived Analogs for the Treatment of Inflammatory and Obstructive Lung Diseases
This innovation relates to analogs/mimetics of CC16 also known as Urinary protein 1 (UPI), or Clara cell protein, or club cell protein. This protein is targeted for the treatment of cancer, chronic obstructive pulmonary disease, asthma, cystic fibrosis and any other diseases that CC16 may have activity in. The inventors have discovered a novel site...
Published: 6/10/2024
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Inventor(s): Julie Ledford, Josef Vagner, Stefano Guerra, Michael Johnson
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary
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Time Resolved Fluorescence based HTS to Detect Structural Changes in cTnI
This innovation involves the development of a probe that attaches to a specific protein called cardiac troponin I (cTnI), which is involved in muscle contraction of the heart. This probe, created through genetic engineering techniques, is designed to detect changes in cTnI's neighboring protein, cardiac troponin T (cTnT). When there's a change...
Published: 5/13/2024
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Inventor(s): Romi Castillo, Jil Tardiff
Keywords(s):
Category(s): Technology Classifications > Research Tools, Technology Classifications > Sensors & Controls > Biologic, Technology Classifications > Life Sciences > Biologics, Technology Classifications > Healthcare Portfolios > Heart and Vascular
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ARTHUR (Autonomous Remote Telesurgery for Healing in Underserved Regions)
This invention introduces the ability to perform laser-based wound debridement remotely using computer vision and AI. The invention pioneers the remote execution of such procedures, offering a glimpse into a future where medical interventions can be conducted from a distance, potentially revolutionizing healthcare accessibility and efficiency. This...
Published: 9/5/2024
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Inventor(s): Geoffrey Gurtner
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity, Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Mobile Application, Technology Classifications > Software & Information Technology > Human Machine Interface
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Natural Compounds including Myrosinase to Treat Alzheimer's Diseases
This invention includes natural compounds for therapeutic use in patients suffering from Alzheimer’s Disease. The inventors have applied computational approaches to existing rich data sets generated by the Accelerating Medical Partnership-Alzheimer's disease consortia to discover novel targets. There are natural compounds which have shown...
Published: 7/6/2023
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Inventor(s): Rui Chang
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Healthcare Portfolios > Neurology
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Myofilament Based Therapeutics for Cardiac Muscle Arrhythmias and Skeletal Muscle Tremors
This invention describes a novel therapeutic approach to treat cardiac muscle arrhythmias and skeletal muscle tremors.
Background:
Cardiac arrhythmias, such as those that cause atrial fibrillation or sudden cardiac death (SCD), are typically viewed as electrical/conduction abnormalities that drive uncoordinated heartbeats and their downstream health...
Published: 7/26/2024
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Inventor(s): Samantha Harris
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences
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Materials Selection Criteria for Electrochemical Sensing Using Organic Electrochemical Transistor (OECT)
This technology is a new method for selecting materials when designing organic electrochemical transistors (OECTs). This method aides the design of OECT-based sensors, enabling optimization for operating power level and sensitivity.
Background:
OECTs are transistors useful in sensing and bioelectronics because they are simple, easy to manufacture,...
Published: 3/12/2024
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Inventor(s): Erin Ratcliff, Songyan Yu
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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Design Guideline of Floating Gate Electrolyte-Gated Transistor (FGEGT) Sensors
This technology is a method for designing floating gate electrolyte-gated transistor-based sensors, so that the sensor achieves a maximum sensitivity while maintaining a low operating voltage.
Background:
Electrolyte-gated transistors (EGTs) are a type of transistor particularly useful in biosensors due to their simplicity, sensitivity, low voltage...
Published: 3/12/2024
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Inventor(s): Erin Ratcliff, Songyan Yu
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Biologics
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Enhanced Melanoma Cancer Prevention by Novel Melanotropins
This invention describes a method to stimulate natural production of melanin in the body. This stimulation is provided by a selective gamma-melanocyte stimulating hormone derivative, which incites the increase in melanin in the body. A natural increase confers photo protective properties without the need for UV activation, making it a safe compound.
Background:
Existing...
Published: 3/12/2024
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Inventor(s): Minying Cai, Victor Hruby
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biologics
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