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C41 Analogs
This invention relates generally to neurodegenerative diseases and conditions, such as Alzheimer’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 9/24/2024
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Inventor(s): Wei Wang, Rui Chang, Vijayan Ramachandran, Patrick Ronaldson
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Biologics
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Natural Compounds including Myrosinase to Treat Alzheimer's Diseases
This invention includes natural compounds for therapeutic use in patients suffering from Alzheimer’s Disease. The inventors have applied computational approaches to existing rich data sets generated by the Accelerating Medical Partnership-Alzheimer's disease consortia to discover novel targets. There are natural compounds which have shown...
Published: 7/6/2023
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Inventor(s): Rui Chang
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Healthcare Portfolios > Neurology
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Sex and APOE Genotype Precision Therapeutic Targets Discovery for Alzheimer’s Disease
This technology encompasses a formulation for patient subgroup-specific supplement for the treatment and therapy of Alzheimer's and other neurodegenerative diseases. These formulations can range in delivery method (food, drink, pill) and can be specific to patient subgroups.
Background:
Alzheimer’s disease is a progressive, neurodegenerative...
Published: 4/24/2024
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Inventor(s): Rui Chang, Roberta Brinton, Rima Kaddurah-Daouk
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences
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Novel Compounds Inhibiting COVID-19 Replication
This technology is three potential pharmacological treatment options for COVID-19. The inventors identified three compounds, two naturally occurring and one small-molecule. These compounds target and inhibit the main 3CL protease that is essential to the replication of SARS-CoV-2 and have been shown to be effective against the virus in vitro.
Background:
In...
Published: 4/3/2023
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Inventor(s): Rui Chang, Dominik Schenten, Patrick Ronaldson, Yanyun Liu, Vijayan Ramachandran
Keywords(s):
Category(s): Technology Classifications > Life Sciences
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Combinations for the Treatment of Neurodegeneration
Researchers at the University of Arizona have researched new formulations and combinations of compounds for the treatment of Alzheimer’s disease. Developing a novel computational system allowed the inventors to identify several therapeutic targets of single cell type and whole bulk tissue that contribute to Alzheimer's disease. These therapeutic...
Published: 4/3/2023
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Inventor(s): Rui Chang, Patrick Ronaldson, Wei Wang, Vijayan Ramachandran, Yanyun Liu, Qianying He
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Life Sciences
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