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Novel Compounds Inhibiting COVID-19 Replication

This technology is three potential pharmacological treatment options for COVID-19. The inventors identified three compounds, two naturally occurring and one small-molecule. These compounds target and inhibit the main 3CL protease that is essential to the replication of SARS-CoV-2 and have been shown to be effective against the virus in vitro. Background: In...

Published: 4/3/2023 | Inventor(s): Rui Chang, Dominik Schenten, Patrick Ronaldson, Yanyun Liu, Vijayan Ramachandran

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Category(s): Technology Classifications > Life Sciences

Combinations for the Treatment of Neurodegeneration

Researchers at the University of Arizona have researched new formulations and combinations of compounds for the treatment of Alzheimer’s disease. Developing a novel computational system allowed the inventors to identify several therapeutic targets of single cell type and whole bulk tissue that contribute to Alzheimer's disease. These therapeutic...

Published: 4/3/2023 | Inventor(s): Rui Chang, Patrick Ronaldson, Wei Wang, Vijayan Ramachandran, Yanyun Liu, Qianying He

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Category(s): Technology Classifications, Technology Classifications > Life Sciences