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Organ-on-Chip Apparatus for Quantitative Study of Cellular Interaction with Ultrasound
This is an organ-to-chip device that is constructed by using thin membranes. The device allows quantitative in vitro modeling of cellular interactions by using ultrasound. The technology also has a large potential for therapeutic applications for treating different diseases. The flexibility of organ-on-chip technologies is a great tool to help speed...
Published: 11/6/2024
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Inventor(s): Jian Gu, Adam Akkad, Frederic Zenhausern
Keywords(s):
Category(s): Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences
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Tools And Techniques To Identify Antigen-Specific T Cells
This invention is a new tool and technique for identification of antigen-specific t cells. By using specific molecules from specified cell lines as antigen presenting cells, the identified T cells are labeled with different fluorescence. These cells go through the flow cytometry and the flow cytometry data is analyzed by a specific assay designed by...
Published: 11/1/2024
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Inventor(s): Michael Kuhns, Bradley Moffett, Caleb Kim, Mark Lee
Keywords(s):
Category(s): Technology Classifications > Research Tools > Screening assays, Technology Classifications > Life Sciences
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Automatic Toilet Disinfectant Dispenser for Public Toilets
This invention is an innovative automatic disinfectant dispenser designed for use in public restrooms. This simple yet effective device aims to reduce the risk of disease transmission by ensuring consistent sanitation of toilet surfaces. The dispenser releases a controlled amount of disinfectant, such as sodium hypochlorite (bleach) tablets, which are...
Published: 8/26/2024
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Inventor(s): Charles Gerba
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Energy, Cleantech & Environmental > Air/Water Purification
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Container Therapeutics at Point of Care
This technology is an innovative method and system for streamlining the production of therapeutic delivery systems. Central to this innovation is the integration of various stages of production, from raw material collection to final product delivery, within a mobile infrastructure. A key embodiment involves the utilization of a container-like structure...
Published: 6/24/2024
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Inventor(s): Frederic Zenhausern
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture, Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics
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CPS1 Markerless Deletion Mutant as a Method for Marker Deletion
This technology involves a novel system using a two-step process to eliminate a gene of interest by incorporating a “suicide gene” vector system. The construct created by this method results with no foreign sequences, making the strains markerless mutants. This means that one has the potential to make genetic strains with multiple mutations...
Published: 5/24/2024
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Inventor(s): Maria Alejandra Mandel, Marc Orbach
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Research Tools > Screening assays
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Chemistry by Design
Title: Chemistry by DesignInvention: This invention is a custom database of worldwide approved pharmaceutical structures, including the United States FDA, that are available for use via a commercial app.Background: Any substance, or mixture of substances, that is planned to be an active ingredient for a drug product is classified as an active pharmaceutical...
Published: 3/12/2024
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Inventor(s): Jon Njardarson
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Software & Information Technology > Bioinformatics, Technology Classifications > Research Tools
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New Deuterated Amino Acid Derivatives
Compositions and methods of making involve the use of alternative acids as reactants instead of carboxylic acids, which produce deuterated amino acids, while carboxylic acids can only synthesize alkyl amino acids. Introducing deuterium to amino acids and derivatives improves biologically active compounds and therapeutics. Modification improves properties...
Published: 6/6/2024
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Inventor(s): Wei Wang, Yue Dong
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Materials > Biomaterials, Technology Classifications > Life Sciences
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Human Serum Albumin-Transgenic Mouse
A novel human albumin transgenic mouse model was developed which can be used to establish human protein biomarkers of exposure to hazardous xenobiotics for human risk assessment via animal studies. This can provide a unique in vivo tool for the assessment of risks of toxicity associated with human exposure to environmentally hazardous chemicals and...
Published: 1/10/2024
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Inventor(s): Xinxin Ding
Keywords(s):
Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Life Sciences
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A Method of Treating Cardiomyopathy
This innovation is based on the finding that lack of Leiomodin-2 (Lmod2) is associated with cardiovascular issues, specifically enlarged heart or cardiomyopathy and it is better to have a truncated/mutated Lmod2 than zero or little Lmod2 present. A premature stop codon associated with Lmod2 causes truncation of Lmod2. This innovation is the use of antisense...
Published: 6/24/2024
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Inventor(s): Christopher Pappas
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Life Sciences, Technology Classifications > Healthcare Portfolios
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Enhancing Absorption of Dietary Compounds to Promote Health
This innovation is directed to oral co-administration of glucuronidase and polyphenols for reabsorption in the gut. Glucuronidase are enzymes that can be made or derived from any source such as bacteria, recombinant, species agnostic, and others. The inactive glucuronides are cleared from the body by secretion back into the gastrointestinal track where...
Published: 10/2/2023
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Inventor(s): Janet Funk
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Healthcare Portfolios
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