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Highly Accelerated and High-Resolution T1-Weighted MRI
This invention is for an accelerated, high-resolution T1-weighted magnetic resonance imaging (MRI) via modification of the three-dimensional magnetization-prepared rapid gradient echo (3D MP-RAGE) sequence. Through this modification, optimization is achieved by allowing for faster signal collection and shorter acquisition time with generation of optimal...
Published: 3/24/2025
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Inventor(s): Silu Han, Nan-kuei Chen
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Radiology, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Neurology
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Acoustic Radiation Force Impulse Procedures for Modulating Glial Cells and Neurons in the Central Nervous System
This technology leverages focused ultrasound and Acoustic Radiation Force Impulse (ARFI) techniques to improve brain health by normalizing synaptic activity and enhancing waste clearance in the central nervous system. It provides two non-invasive procedures: one targets astrocytes to modulate synaptic activity, while the other stimulates the glymphatic...
Published: 3/24/2025
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Inventor(s): Nan-kuei Chen
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Sensors & Controls > Motion & Force, Technology Classifications > Medical Devices > Therapeutic
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Placement of Spinal Cord Stimulation Leads
This technology focuses on improving spinal cord stimulation (SCS) treatments by helping physicians determine the optimal placement of stimulation leads on the body. The approach utilizes a specialized algorithm designed to predict the best lead locations for achieving effective pain relief and improved clinical outcomes. By integrating advanced imaging...
Published: 12/16/2024
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Inventor(s): Julie Pilitsis, Ilknur Telkes, Nan-kuei Chen, Mitchell Bartlett
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Musculoskeletal Disorders, Orthopedics/Bone, Technology Classifications > Life Sciences, Technology Classifications > Medical Devices > Therapeutic, Technology Classifications > Software & Information Technology > Health IT
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Flyback Echo-Planar Imaging (EPI) Pulse Sequence with Embedded Chemical-Shift and Field Inhomogeneity Compensation Schemes and Artifact-Free Image Reconstruction Procedures
This technology produces echo-planar imaging (EPI) MRI data free from typical EPI artifact (e.g., Nyquist artifact; chemical-shift artifact; geometric distortion) via two interrelated components. The first is a new algorithm that is used to acquire flyback echo-planar imaging (EPI) data, in which chemical-shift artifact and magnetic field inhomogeneity...
Published: 3/19/2025
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Inventor(s): Nan-kuei Chen
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Healthcare Portfolios > Radiology
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Novel Multi-Omics Aging Clock
A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...
Published: 3/12/2024
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Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools
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Spectral-Tagging Technique for Improving Resolution of Dynamic Echo-Planar Imaging
This invention is a spectral-tagging method that allows for 3X faster speed of acquisition with improved resolution of the targeted physiology. The invention improves upon echo-planar imaging by band-pass filtering different signals to reconstruct a specific spectral peak, resulting in high quality images without aliasing artifacts from multi-band echo-planar...
Published: 8/1/2024
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Inventor(s): Nan-kuei Chen
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Electronics > Mixed Signal Processing, Technology Classifications > Imaging & Optics > Medical Imaging
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