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ERG-7 Inhibitors: Targeting the Sterol Biosynthetic Pathway
This invention relates to small molecule anti-fungal compounds, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of fungal diseases in human and veterinary subjects. In particular aspects, the invention provides inhibitors that modulate fungal sterol biosynthesis, including inhibitors of lanosterol synthase...
Published: 5/6/2026
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Updated: 5/6/2026
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Inventor(s): Rui Xiong, Hongmin Li, Malla Reddy Gannarapu, Divakar Indukuri, Anil Tharappel, Ke Chen, Mengjiao Ma
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
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nsP2 Inhibitors: Targeting the Alphavirus nsP2 Protease
This invention relates to antiviral compounds targeting the alphavirus nsP2 protease, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of the Chikungunya virus. This compound selectively interferes with the essential proteolytic processing activity of nsP2, a critical step in the viral life cycle. By blocking...
Published: 4/29/2026
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Updated: 4/29/2026
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Inventor(s): Hongmin Li, Rui Xiong, Subodh Samrat, Malla Reddy Gannarapu, Ran Zhang, Ke Chen, Mengjiao Ma, Omar Alejandro Lozano Ramos, Divakar Indukuri, Renu Bhardwaj
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules
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UWB-PostureGuard: A Privacy-Preserving RF Sensing System for Continuous Ergonomic Sitting Posture Monitoring
UWB-PostureGuard is an ergonomic posture monitoring technology that continuously detects sitting posture without cameras or wearable devices, while preserving user privacy. The technology is designed for real-time use in everyday desk and seated work environments, providing posture awareness and enabling timely feedback when sustained or potentially...
Published: 4/28/2026
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Updated: 4/28/2026
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Inventor(s): Haotang Li, Zhenyu Qi, Sen He, Kebin Peng, Sheng Tan, Yili Ren, Tomas Cerny, Jiyue Zhao, Zi Wang
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Human Machine Interface, Technology Classifications > Healthcare Portfolios, Technology Classifications > Imaging & Optics > Sensors and Detection > Remote Sensing
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Vox Deorum
This technology is a hybrid large language model (LLM) that connects artificial intelligence (AI) agents into open source 4X and grand strategy games. Vox Deorum enables the observation and comparison of reasoning and decision-making across different AI agents within a game environment, while also facilitating interaction between human players and AI...
Published: 4/13/2026
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Updated: 4/13/2026
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Inventor(s): John Chen
Keywords(s):
Category(s): Technology Classifications > Creative Works & Copyright, Technology Classifications > Software & Information Technology > Open Source
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Topological Acoustic Synapse for High-Dimensional Neuromorphic Computing
The Topological Acoustic Synapse is a neuromorphic hardware device that uses acoustic waves to perform high-dimensional neuromorphic computing. The device encodes information in a multivariate state space and uses nonlinear acoustic wave interactions to reproduce synapse-like behavior for computation. By shifting key functions from purely electronic...
Published: 2/3/2026
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Updated: 2/3/2026
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Inventor(s): Xiaodong Yan, Jinli Chen, Akinsanmi Ige, Pierre Deymier, Keith Runge
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Electronics
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CD64+ AND CD14+ Cell Replacement Therapy for Wound Healing
This technology is a cell-based therapy involving an administered dose of cells expressing both CD64+ and CD14+ ligands. It is designed to promote healing in diabetic patients, with potential to reduce inflammation and support tissue regeneration. The cells can be observed in tissue, blood, and bone marrow, allowing for broader variety in addressing...
Published: 3/18/2026
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Updated: 9/15/2025
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Inventor(s): Geoffrey Gurtner, Kellen Chen, Katharina Berryman, Maria Gracia Mora Pinos
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity, Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
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Snapshot Wavefront Camera
This invention is a reference-free snapshot wavefront camera that can be used to measure both amplitude and phase of the wavefront. The camera uses a two-dimensional diffraction grating to split the incoming wavefront into multiple copies which then travel through a lens that focuses them onto a sensor in a camera array. The resulting wavefront information...
Published: 7/2/2025
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Updated: 7/2/2025
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Inventor(s): David Brady, Ni Chen, Shengtai Zhu, Gregory Nero
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Imaging & Optics > Ophthalmology
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Universal Fault Tolerant Quantum Computation with Trotter Circuits
This invention introduces a novel approach to implementing fault-tolerant quantum circuits using Trotter circuits, which are essential for quantum simulations and other key algorithms. It provides a systematic framework for translating logical Trotter circuits into physical ones using symplectic transvections—algebraic structures that ensure the...
Published: 6/30/2025
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Updated: 6/30/2025
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Inventor(s): Zhuangzhuang Chen, Narayanan Rengaswamy, Jack Owen Weinberg
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Quantum, Technology Classifications > Engineering & Physical Sciences > Communications & Networking
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Personalized Motion Prediction for Enhanced Performance and Safety
This technology leverages artificial intelligence (AI) and motion capture to analyze and predict human movement patterns. Using video-based tracking and sensor data, it creates a personalized digital model of an individual’s biomechanics in different movements (e.g. sitting, walking, squatting, other functional movements, etc.). This model can...
Published: 7/22/2025
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Updated: 4/21/2025
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Inventor(s): Kavan Hazeli, Ziao Chen
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Education & Training, Technology Classifications > Healthcare Portfolios > Physical Medicine & Rehabilitation
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Highly Accelerated and High-Resolution T1-Weighted MRI
This invention is for an accelerated, high-resolution T1-weighted magnetic resonance imaging (MRI) via modification of the three-dimensional magnetization-prepared rapid gradient echo (3D MP-RAGE) sequence. Through this modification, optimization is achieved by allowing for faster signal collection and shorter acquisition time with generation of optimal...
Published: 4/21/2026
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Updated: 3/24/2025
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Inventor(s): Silu Han, Nan-kuei Chen
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Radiology, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Neurology
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