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CD64+ AND CD14+ Cell Replacement Therapy for Wound Healing
This technology is a cell-based therapy involving an administered dose of cells expressing both CD14+ and CD64+ ligands. It is designed to promote healing in diabetic patients, with potential to reduce inflammation and support tissue regeneration. The cells can be observed in tissue, blood, and bone marrow, allowing for broader variety in addressing...
Published: 9/15/2025
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Inventor(s): Geoffrey Gurtner, Kellen Chen, Katharina Berryman, Maria Gracia Mora Pinos
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity, Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
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A Method of Treating Fibrosis and Cancer across Organ Systems
This technology is directed to a method of treating fibrosis and cancer by targeting circulating cells. Researchers identified mechanoresponsive myeloid subpopulations present in fibrotic and healthy tissue. Certain subpopulations of circulating cells have been implicated in the processes of cancer and fibrosis. These subpopulations are subsequently...
Published: 4/25/2024
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Inventor(s): Geoffrey Gurtner, Kellen Chen
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Wound Healing, Technology Classifications > Life Sciences > Therapeutics
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Novel Multi-Omics Aging Clock
A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...
Published: 3/12/2024
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Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools
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