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Fluorinated Poly (β-Amino Ester) Nanoparticle for Highly Efficient and Specific Delivery of Nucleic Acids to the Lung Capillary Endothelium
This technology describes nanoparticles with specific structure design and modification for high efficiency and specific delivery of nucleic acids to the pulmonary endothelial cells. After intravenous administration, the nanoparticles were capable of delivering non-integrating DNA plasmids to lung microvascular endothelial cells but not to other lung...
Published: 2/6/2024
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Inventor(s): Zicheng Deng, Vladimir Kalinichenko, Donglu Shi
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Drug Delivery
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Mini-Sensor Suspension System for Supine CO2 Monitoring
University of Arizona researchers have developed a non-invasive device that measures carbon dioxide (CO2) concentration around a person’s face, which has important implications for patients in hospitals and treatment centers. By collecting and analyzing the respiratory gases around a supine subject’s face, the system can provide insights...
Published: 1/3/2024
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Inventor(s): Yijie Chen, Md Tariqul Islam, Young-Jun Son, Esther Sternberg, Christopher Morton
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Medical Devices
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Covid-19 Time of Intubation Mortality Evaluation (C-TIME)
This invention describes software that uses a scoring system for calculating the probable mortality of patients with COVID-19 pneumonia at the time they require mechanical ventilation.
Background:
Worldwide there have been over 208 million cases of severe acute respiratory coronavirus 2 (SARS-CoV-2) and over 4.37 million of these cases resulted in...
Published: 5/10/2023
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Inventor(s): Craig Heise, Robert A. Raschke, Pooja Rangan, Sumit Agarwal, Suresh Uppalapu, Nehan Sher
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Healthcare Portfolios > Emergency Medicine
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Method, System and Devices for Defining Respiratory Status
This invention is a system comprising FDA-approved MC10 BioStamp wearable sensors to gauge respiratory health in patients. The sensors are applied directly to the skin and can be used to produce gyroscopic data, including information around muscle activation and sleep. The data can be cross-referenced with observations from a motion capture system....
Published: 6/28/2023
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Inventor(s): Marvin Slepian
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary
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Virtual Reality Simulation for Airway Management
This invention is a dual haptic-virtual reality task training system for medical students and/or professionals learning tracheal tube intubation. This technology combines the current training method and a mannequin with VR/AR and a haptic feedback and force measuring system. By creating a medical training system with a more life-like simulation, users...
Published: 2/1/2024
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Inventor(s): Jarrod Mosier, Young-Jun Son, David Biffar, Vignesh Subbian, Saurabh Jain, Bijoy Dripta Barua Chowdhury, Thomas Cahir, Eze Ahanonu
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Ear, Nose, & Throat, Technology Classifications > Healthcare Portfolios > Health Education, Medical Training and Operations, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Imaging & Optics > Medical Imaging
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Innovative Approaches to Optimize the Therapeutic Benefit of Autophagy Inhibition
This invention is a set of novel synthetic compounds that demonstrate autophagy-inhibiting efficacy, useful for cancer and pulmonary hypertension treatment.
Background:
Autophagy is an evolutionarily conserved lysosomal protein degradation process. Aberrant autophagy plays a role in the pathogenesis of many health conditions including cancer, pulmonary...
Published: 4/3/2023
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Inventor(s): Jennifer Carew, Steffan Nawrocki, Wei Wang
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Therapeutics
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A New Device to Treat Pulmonary Arterial Hypertension (PAH) Through Neuromodulation
This invention is a method of treating pulmonary arterial hypertension without the use of drugs. The invention describes a system for bilateral electrical stimulation of the vagus nerve that can be implanted in the human body with the goal of ameliorating symptoms of pulmonary arterial hypertension. This device can be used with neonatal populations,...
Published: 4/3/2023
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Inventor(s): Mohamed Ahmed, Philipp Gutruf
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Medical Devices > Therapeutic
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Proteins from Asthma-Protective Amish Farm Dust
This technology involves eight proteins that have been identified from fractions of Amish farm dust, which have been shown to protect against asthma in mice models. These eight proteins consist mainly of environmental allergens that can induce an immune response and have the potential to be utilized for allergen immunotherapy to help protect against...
Published: 11/16/2023
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Inventor(s): Fernando Martinez, Donata Vercelli, Shane Snyder, Erika VonMutius, Mauricius Marques dos Santos, Vadim Pivniouk
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Therapeutics
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A New Method for Preventing and/or Treating Asthma and Related Respiratory Conditions
This technology is an intranasal and/or inhaled therapeutic that consists of a bacterial extract. Initial studies have shown that it protects against characteristic asthma phenotypes such as airway hypperresponsiveness, bronchoalveolar lavage eosinophillia, and increased expression of type-2 cytokines in the lung. The therapy can protect against various...
Published: 11/16/2023
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Inventor(s): Donata Vercelli, Fernando Martinez, Vadim Pivniouk, Christian Pasquali, Jacques Bauer
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary
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Improved Inferior Vena Cava Filter
This technology is an improved inferior vena cava (IVC) filter that allows for adjustments during deployment to prevent tilting of the filter within the inferior vena cava.
Background:
An IVC filter is used to prevent pulmonary embolism in patients who have built up thrombosis. However, a large percentage of IVC filters cannot be retrieved at a...
Published: 4/3/2023
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Inventor(s): Craig Weinkauf
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Medical Devices
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