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Graph Theory Based Least Squares Optimization Algorithm for Behavioral Estimation (G.L.O.B.E.)
This is an advanced software tool that analyzes functional neuroimaging data to map brain oscillations and predict optimal task timing across cognitive domains. By integrating MRI-based connectivity data with user input, it provides insight into the understanding of how different brain states interact. This predictive software intends to provide recommendations...
Published: 3/31/2025
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Inventor(s): David Negelspach, William Killgore
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Education & Training
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Highly Accelerated and High-Resolution T1-Weighted MRI
This invention is for an accelerated, high-resolution T1-weighted magnetic resonance imaging (MRI) via modification of the three-dimensional magnetization-prepared rapid gradient echo (3D MP-RAGE) sequence. Through this modification, optimization is achieved by allowing for faster signal collection and shorter acquisition time with generation of optimal...
Published: 3/24/2025
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Inventor(s): Silu Han, Nan-kuei Chen
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Radiology, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Neurology
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Intracranial and Cerebrospinal Fluid Deuteration using Heavy Water Isotopologues
This invention is a method of therapeutic intervention for primary and metastatic brain cancer, and other relevant nervous system derivates, via the deliverances of deuterated heavy water isotopologue. This novel treatment method offers promise for specificity improvements as it uses water to deliver its therapy, allowing for increased efficiency in...
Published: 3/3/2025
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Inventor(s): Georg Wondrak, Jana Jandova
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Therapeutics
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High Efficient Rodent Interspecies Rotational Head Trauma Instrument
This invention is a novel rotational traumatic brain injury (rTBI) model that delivers rotational impacts to the heads of rodents. This technology aims to provide a strong model for research of the pathophysiology of rTBI and help develop therapeutics.
Background:
Many traumatic brain injuries occur in the United States and result from sports accidents,...
Published: 2/17/2025
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Inventor(s): James Bibb, Diana Monge, Julian Ramos
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Research Tools > Animal Models
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Use of MRS to Identify Chronic Injury Post-Stroke
This invention involves using magnetic resonance spectroscopy (MRS) to identify lipid-laden foam cells to diagnose a chronic stroke injury. This technology is specifically meant for monitoring patients post-stroke brain injury. This largely relates to improving management patient care and advancing stroke therapeutics.
Background:
Currently, MRS...
Published: 2/10/2025
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Inventor(s): Helena Morrison, Theodore Trouard
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Diagnostics
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C41 Analogs
This invention generally relates to neurodegenerative diseases and conditions, such as Alzheimer’s disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 12/5/2024
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Inventor(s): Wei Wang, Rui Chang, Vijayan Ramachandran, Patrick Ronaldson
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Biologics
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Off-Label Use of an Anti-Hypertensive to Treat Epilepsy
University of Arizona researchers have found the angiotensin II receptor blocker, Candesartan, to effectively reduce epileptic activity.
Background:
As the most prevalent neurological disease, epilepsy is estimated to affect around 50 million people worldwide. In the United States, it is estimated that around 470,000 children and 3 million adults...
Published: 11/14/2024
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Inventor(s): Michael Hammer, Erfan Bahramnejad
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Therapeutics
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Myelin Breakdown Products as Plasma Biomarkers of Therapeutic Efficacy in the Acute Phase after Stroke
This invention pertains to the use of myelin breakdown products, such as lipids indicative of brain lipid catabolism, as plasma biomarkers for the diagnosis and prognosis of ischemic stroke (IS). Researchers discovered an acute signature of brain lipid catabolism in the plasma 24 hours after a stroke in mouse model research. Notably, a substantial proportion...
Published: 8/12/2024
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Inventor(s): Kristian Doyle, Danielle Becktel
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Biomarkers
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Arachidonic Acid Derivatives as Plasma Biomarkers of Chronic Inflammation After Stroke
This invention pertains to the use of arachidonic acid derivatives as plasma indicators for the diagnosis and prognosis of inflammation, including chronic inflammation, following ischemic stroke (IS). Researchers have identified novel plasma biomarkers indicative of neurodegeneration and inflammation in a mouse model of stroke, with particular emphasis...
Published: 8/12/2024
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Inventor(s): Kristian Doyle, Danielle Becktel
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Biomarkers
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Diagnostic Tool for Identifying Delirium using Electronic Medical Records
Neurologic, Orientation and Verbal Assessment of Delirium (NOVAD) is a smart-EMR screening tool designed to detect delirium in hospitalized adults. NOVAD leverages assessments that nurses are already familiar with to provide an early warning system for delirium detection, empowering healthcare professionals with actionable insights, leading to timely...
Published: 7/10/2024
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Inventor(s): Nimit Agarwal, Sumit Agarwal
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Medical Devices > Diagnostic
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