Search Results - james+bibb

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High Efficient Rodent Interspecies Rotational Head Trauma Instrument
This invention is a novel rotational traumatic brain injury (rTBI) model that delivers rotational impacts to the heads of rodents. This technology aims to provide a strong model for research of the pathophysiology of rTBI and help develop therapeutics. Background: Many traumatic brain injuries occur in the United States and result from sports accidents,...
Published: 2/17/2025   |   Inventor(s): James Bibb, Diana Monge, Julian Ramos
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Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Research Tools > Animal Models
Rotational Force-Induced Brain Injury Model
This innovation is a new instrument, model, and treatment for repetitive rotational head trauma in rodents that demonstrates the acute and prolonged pathological, behavioral, and electrophysiological effects of rotational traumatic brain injury (rTBI). Aberrant Cyclin-dependent kinase 5 (Cdk5) activity is a principal mediator of rTBI. Cdk5-enriched...
Published: 6/20/2024   |   Inventor(s): James Bibb, Alan Umfress
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Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Life Sciences > Therapeutics