|
Isolation of Protein Biomarkers from Saliva as a Technology to Assess and Monitor Cardiac Infarction
This technology introduces a novel separation method designed to isolate small protein biomarkers directly from saliva, enabling a rapid and non-invasive diagnostic approach for cardiac infarction. The system employs a hybrid chromatographic matrix that selectively rejects large proteins while allowing smaller biomarkers to interact with affinity sites...
Published: 11/24/2025
|
Inventor(s): Roberto Guzman, David Mier-Salazar, Christopher Rodriguez
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
|
|
Novel Mechanism-Based Therapy for Aortic Stiffening and Related Cardiovascular and Cerebrovascular Disorders
This invention involves a novel mechanism-based therapy by using a small molecule compound to reduce aging and hypertensive aortic stiffening, subsequently improve blood pressure (BP) control in resistant hypertension patients and prevent or reverse pathologies of vascular cognitive impairment and dementia (VCID) and Alzheimer’s Disease (AD)....
Published: 11/24/2025
|
Inventor(s): Hongyu Qiu
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
|
|
Repurposing the FDA-Approved Antibody to Treat Aortic Stiffening and Resistant Hypertension
This innovation repurposes an FDA-approved antibody to treat and prevent aortic stiffening and resistant hypertension (RH). This mechanism-based therapeutic, inhibits receptor mediated inflammatory and pro-stiffness signaling to reduce aortic stiffness and improve blood pressure control, ultimately breaking the root cycle of hypertension.
Background:...
Published: 11/24/2025
|
Inventor(s): Hongyu Qiu
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Therapeutics
|
|
Pioneering Cell-Based Solutions for Vascular Aging
This invention is a mechanism-based cell therapy for treating aortic stiffening, particularly in cases of old hypertension patients that do not respond to current treatments. It is also intended to help prevent cardiovascular disease and promote healthy aging in older populations.
Background:
Aortic stiffening is a critical age-related risk factor...
Published: 9/15/2025
|
Inventor(s): Hongyu Qiu, Liwu Li
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Therapeutics
|
|
AI-Enhanced Wearable Multi-Microphone Fetal Heart Rate Monitoring Belt with Maternal Heart Rate Differentiation
This invention is for a wearable belt encapsulating a fetal heartrate monitoring device (FHR). It employs a multi-microphone array for differentiation of maternal and feta heartbeats and utilizes data from real-time signal processing in conjunction with AI to achieve precise fetal monitoring. The device features wireless connectivity, transmitting real-time...
Published: 8/13/2025
|
Inventor(s): Ravi Goyal
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices
|
|
Companion Diagnostic for Immunomodulatory Repair Treatments
This technology is a diagnostic tool designed to help match patients to specific drugs or therapies to treat chronic ischemic heart failure. The platform focuses on immune cells called macrophages, which play a crucial role in the body's response to injury and disease. By promoting a specific type of macrophage known to aid healing, this system...
Published: 5/30/2025
|
Inventor(s): Steven Goldman, Daniel Benson, Adrian Grijalva, Jordan Fink, Jordan Lancaster, Jennifer Koevary, Simar Singh
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Healthcare Portfolios > Heart and Vascular
|
|
Chimetic Antigen Receptor (CAR)-Stem Cells (MSCs) and its use for Cardiovascular Diseases
This technology describes Chimetic Antigen Receptor (CAR) mesenchymal stem cells (MSCs) and their use in treatment of cardiovascular diseases. This technology will use engineered MSCs capable of homing toward infarcted heart tissue.
Background:
Cardiovascular disease is the leading cause of death in the United States. There are multiple treatments...
Published: 1/7/2025
|
Inventor(s): Youngwook Won, Byeong Hyun Cha, David Bull
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Stem Cells, Technology Classifications > Life Sciences > Therapeutics
|
|
Custom Coded Raspberry Pi Pico to Induce Atrial Fibrillation in Swine
This invention is a low cost, reproduceable device designed to reproduce atrial fibrillation (AFib) in swine to create a large animal model of persistent AFib. Using a Raspberry Pi Pico microcontroller to burst pace, this device allows for more modularity and can be programmed with many common programming languages. This large animal model can help...
Published: 1/21/2025
|
Inventor(s): Steven Goldman, Fox Bravo, Adrian Grijalva, Talal Moukabary, Alan Salciccioli
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Heart and Vascular
|
|
Factor XII(a) is a Biotarget for Treatment of Dilated Cardiomyopathy and Heart Failure
Researchers at the University of Arizona have identified a novel, previously unrecognized harmful role of coagulation factor, Factor XII (FXII) and/or activated coagulation factor XIIa (fXII(a)) in modulating the progression of dilated cardiomyopathy and heart failure development. They have proposed fXII(a) as a new biotarget to treat dilated cardiomyopathy...
Published: 12/4/2024
|
Inventor(s): Guy Reed, Inna Gladysheva, Ryan Sullivan
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Heart and Vascular
|
|
Applications of Deuterated Aldehydes and Isonitriles
This innovation is a novel method of synthesizing calcium channel blockers, with applications to extend the half-life of heart disease medications. This can be used as building blocks to create new pharmaceuticals or potentially used to expand the lifespan of current medications. It has applications to site specific calcium-channel blocking that can...
Published: 6/7/2024
|
Inventor(s): Christopher Hulme, Wei Wang, Kevin Schofield, Yueteng Zhang
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Heart and Vascular
|
