|
Mechanism of Tissue Regeneration
This invention is a biodegradable patch seeded with human neonatal dermal fibroblasts and human induced pluripotent stem cell derived cardiomyocytes which helps regenerate endogenous cardiomyocytes in adult murine, rat, and swine models of myocardial infarction as a cause of chronic heart failure (CHF). This invention details changes in specific gene...
Published: 9/24/2024
|
Inventor(s): Steven Goldman, Jennifer Koevary, Jordan Lancaster, Jordan Fink, Adrian Grijalva
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Regenerative Medicine / Tissue Engineering, Technology Classifications > Life Sciences > Therapeutics
|
|
Clinical ECG Parameters from a Bioengineered Human Cardiac Tissue
This technology consists of a bioengineered cardiac tissue that exhibits electrocardiogram parameters and can be used in screening cardiotoxicity and proarrhythmic potential.
Background:
Currently, pharmaceutical compounds must be screened for cardiotoxicity using in vitro testing and animal models. However, current cell-based methods rely on cell...
Published: 4/3/2023
|
Inventor(s): Ikeotunye Chinyere, Jordan Lancaster, Jennifer Koevary, Steven Goldman
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Materials > Biomaterials
|
|
Cell Based Therapies for Arrhythmias
This invention is a tissue engineered cardiac patch, which improves left ventricular function. The patch is made from microscopic thin fibers that serve as a scaffold for cells to adhere to.
Applications:
Pharmaceutical industry
Biotechnology and medical device companies
Hospitals
Surgical centers
Research laboratories
Advantages:
Novel...
Published: 8/28/2023
|
Inventor(s): Jordan Lancaster, Steven Goldman, Jennifer Koevary, Ikeotunye Chinyere
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Therapeutics
|
