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Custom Coded Raspberry Pi Pico to Induce Atrial Fibrillation in Swine
This invention is a low cost, reproduceable device designed to reproduce atrial fibrillation (AFib) in swine to create a large animal model of persistent AFib. Using a Raspberry Pi Pico microcontroller to burst pace, this device allows for more modularity and can be programmed with many common programming languages. This large animal model can help...
Published: 1/21/2025
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Inventor(s): Steven Goldman, Fox Bravo, Adrian Grijalva, Talal Moukabary, Alan Salciccioli
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Heart and Vascular
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Mechanism of Tissue Regeneration
This invention is a biodegradable patch seeded with human neonatal dermal fibroblasts and human-induced pluripotent stem cell-derived cardiomyocytes, which helps regenerate endogenous cardiomyocytes in adult murine, rat and swine models of myocardial infarction as a cause of chronic heart failure (CHF). This invention details changes in specific gene...
Published: 2/3/2025
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Inventor(s): Steven Goldman, Jennifer Koevary, Jordan Lancaster, Jordan Fink, Adrian Grijalva
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Regenerative Medicine / Tissue Engineering, Technology Classifications > Life Sciences > Therapeutics
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Clinical ECG Parameters from a Bioengineered Human Cardiac Tissue
This technology consists of a bioengineered cardiac tissue that exhibits electrocardiogram parameters and can be used in screening cardiotoxicity and proarrhythmic potential.
Background:
Currently, pharmaceutical compounds must be screened for cardiotoxicity using in vitro testing and animal models. However, current cell-based methods rely on cell...
Published: 4/3/2023
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Inventor(s): Ikeotunye Chinyere, Jordan Lancaster, Jennifer Koevary, Steven Goldman
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Materials > Biomaterials
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