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Glycopeptide-Lipid Supramolecular Assembly
This invention provides an approach, including compositions and methods for delivering glycopeptides to biological cells. This is done using supramolecular assemblies made of glycopeptides and amphipathic molecules, which may be used to deliver therapeutics, including glycosylated hormones or their analogues, such as endomorphin, dermorphin, angiotensin,...
Published: 6/20/2024
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Inventor(s): Robin Polt, Michael Heien
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Healthcare Portfolios > Neurology
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Low Cost Anesthesiology Monitoring Device for Real Time Animal Physiology Monitoring
This is technology is a portable "electronic anesthesiologist" that is engineered and designed to automate and standardize the collection of respiratory rate in sedated animals.
Background:
Conducting safe surgical procedures in sedated animal subjects or patients requires monitoring of the animal's respiratory rate. For laboratory studies,...
Published: 3/12/2024
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Inventor(s): Michael Heien, Drew Farrell
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation
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Novel Peptides Bioavailable to the Brain for Non-Opioid Pain Relief and/or Addiction Treatment
Inventors at the University of Arizona have developed oxytocin analogues which have high potency, are designed to be more stable compared to the native oxytocin hormone (an endogenous peptide which inhibits pain and promotes social connection), have very high selectivity for oxytocin receptors, and are bioavailable for brain therapeutics. These druggable...
Published: 3/12/2024
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Inventor(s): Lajos Szabo, Robin Polt, John Streicher, Michael Heien, Parthasaradhi Reddy Tanguturi
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Healthcare Portfolios > Neurology > Mental Health, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
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Portable Low-Cost System for Field Chemical Analysis
This invention describes a portable, low cost, system incorporating a compact potentiostat for electrochemical analytical chemistry measurements. The system can run on five-volt batteries and stores data that can be readily exported.
Background:
Measurement science has continually evolved since the introduction of the operational amplifier, the...
Published: 3/12/2024
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Inventor(s): Michael Heien, Drew Farrell
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Electronics, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation
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Neurochemical Data Collection from In vivo Electrochemical Measurements
This invention allows for the collection of real-time chemical analysis of neurotransmitters in the brains of lab animals via rapid application of voltage with resulting current measurement from microelectrodes. Tiny carbon-fiber electrodes are implanted into the animal, and electrochemical measurements are recorded, providing information to relate...
Published: 3/12/2024
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Inventor(s): Michael Heien, Christopher Atcherley
Keywords(s): accuracy
Category(s): Technology Classifications > Research Tools > Animal Models
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Hardware Platform Enabling the Instruction Of Analog Signal Processing Techniques At The Collegiate Level
The proposed technology is an analytical kit for perform analytical chemistry course experiments. This kit is an all-inclusive curriculum platform including compact, integrated hardware with signal processing, data recording, and experimental guide.
Background:
Currently, a large amount of time is used for experimental set-up which is not required...
Published: 3/12/2024
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Inventor(s): Michael Heien, Drew Farrell
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation
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Curriculum Materials for the Education of Graduate Level Measurement Science
This technology is an analytical kit for perform analytical chemistry course experiments. This kit is an all-inclusive curriculum platform including compact, integrated hardware with signal processing, data recording, and experimental guide.
Background:
Currently, a large amount of time is used for experimental set-up which is not required for demonstrating...
Published: 3/12/2024
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Inventor(s): Michael Heien, Drew Farrell, Neal Armstrong, Steven Scott Saavedra, Deirdre Belle-Oudry
Keywords(s):
Category(s): Technology Classifications > Creative Works
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Software Platform for the Collection and Processing of Chemical Data
This patented technology is an analytical kit for perform analytical chemistry course experiments. This kit is an all-inclusive curriculum platform including compact, integrated hardware with signal processing, data recording, and experimental guide.
Background:
Currently, a large amount of time is used for experimental set-up which is not required...
Published: 6/20/2024
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Inventor(s): Michael Heien, Drew Farrell
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Education & Training
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Glycolipid and Mixed Micelle Characterization via Diffusion-Ordered Spectroscopy
This invention is a spectroscopy method to measure and observe solutions such as aggregates for the purpose of characterizing glycolipid surfactants.
Background:
Surfactants are known compounds that lower surface tension between two liquids, or a liquid and a solid, with application in detergents, wetting agents, foams, etc. Most industrial surfactants...
Published: 3/12/2024
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Inventor(s): Dillon Hanrahan, Lajos Szabo, Robin Polt, Michael Heien, Chenxi Liu
Keywords(s):
Category(s): Technology Classifications > Materials, Technology Classifications > Research Tools
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Glycopeptide and Classical Drug Design
This invention relates to the glycosylation drug candidates to increase penetration, bioavailability, and stability.
Background:
Transmembrane proteins provide a pathway for drugs to interact with a cell's interior. Drugs commonly target G-protein coupled receptors (GPCRs), comprising 40% of the market. Peptides and small molecule drugs directed...
Published: 3/12/2024
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Inventor(s): Robin Polt, Christopher Apostol, Michael Heien, Chenxi Liu, John Streicher, Lajos Szabo, Torsten Falk
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Drug Delivery
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