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Therapeutic Nanoparticles for Renal Disease
University of Arizona researchers have developed a technology that uses biodegradable, polymeric nanoparticles to specifically deliver drugs to the kidney, thereby bypassing off target/organ effects. For example, drugs such as formoterol, a beta 2 adrenergic agonist, can be used to treat acute and chronic renal disease. Encapsulation of these drugs...
Published: 12/15/2023
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Inventor(s): Rick Schnellmann, Heidi Mansour, David Encinas Basurto, Ernest Vallorz
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Drug Delivery
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Design and Development of Innovative Formulations of Resatorvid for Targeted Skin Drug Delivery and Applications Therein
University of Arizona researchers have developed a novel formulation of Resatorvid, a selective TLR4 inhibitor that was originally designed for the treatment of sepsis. This re-formulation is designed for delivery to the skin for a variety of skin diseases including early stages of skin cancer.
Background:
Skin cancers tend to be slow growing and can...
Published: 11/16/2023
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Inventor(s): Heidi Mansour, Victor Ruiz, Sally Dickinson, Clara Curiel, Hsiao-Hui Chow, Georg Wondrak
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics
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Synthesis and Characterization of Innovative Formulations of Suramin Hydrogels for Drug Delivery and Applications Therein
This invention consists of new advanced formulations of the drug Suramin for administration by multiple routes. In addition, the invention surrounds the process and manufacturing of these newly formulated Suramin microparticles and nanoparticles so they can be effectively used in the treatment of wounds. Specifically, these new formulations would be...
Published: 11/16/2023
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Inventor(s): Heidi Mansour, Rick Schnellmann, David Encinas Basurto
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences > Therapeutics
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Advanced Engineered Formulations of Suramin Microparticles and Nanoparticles for Drug Delivery and Applications Therein
This invention consists of new advanced formulations of the drug Suramin for administration by multiple routes. In addition, the invention surrounds the process and manufacturing of these newly formulated Suramin microparticles and nanoparticles so they can be effectively used in the treatment of wounds. Specifically, these new formulations would be...
Published: 11/16/2023
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Inventor(s): Heidi Mansour, Rick Schnellmann, Maria Acosta
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Radiology, Technology Classifications > Life Sciences > Drug Delivery
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Advanced Engineered Formulations of Simvastatin and L-Carnitine Microparticle/Nanoparticle Formulations for Inhalation Drug Delivery for Respiratory and Pulmonary Vascular Diseases and Applications Therein
This invention is novel dry powder formulations of simvastatin and L-Carnitine (separately or combined) for inhalation delivery for pulmonary vascular diseases.
Background:
Pulmonary vascular diseases are caused by various reasons and may require combined therapies that act through difference mechanisms. Simvastatin inhibits undesired cholesterol...
Published: 7/26/2024
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Inventor(s): Heidi Mansour, Stephen Black, Maria Acosta
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics
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Advanced Engineered Formulations Of Rho/Rock Kinase Inhibitor (fasudil) Microparticle/Nanoparticle Formulations For Inhalation Drug Delivery For Respiratory And Pulmonary Vascular Diseases And Applications Therein
This technology is the reformulation of fasudil, a known pharmaceutical, into a dry powder form to facilitate non-invasive, aerosolized administration of the medication. This affords a localized, potent and increased availability of the drugs to the body. The intended purpose of this formulation is to treat pulmonary hypertension and other pulmonary...
Published: 7/26/2024
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Inventor(s): Heidi Mansour, Stephen Black, Priyadarshini Muralidharan
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Drug Delivery
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Advanced Engineered Formulations of TMP/Ligustrazine and Microparticle/Nanoparticle Formulations for Inhalation Drug Delivery for Lung Vascular, Interstitial and Airway Diseases
This invention formulates Tetramethylpyrazine (TMP) in a readily deliverable aerosol to treat pulmonary hypertension and other lung diseases.
Background:
Pulmonary hypertension (PH) is a condition that involves high blood pressure in the arteries of the lungs. Veins stiffen and narrow, making blood flow more difficult and thus, increased pressure...
Published: 11/16/2023
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Inventor(s): Heidi Mansour, Jason Yuan, Jian Wang, Alexan Gomez, Priyadarshini Muralidharan, Yali Gu
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics
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