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A Novel Chemical Entity, Mary1, for the Treatment Mitochondrial Dysfunction, Vascular Injury, Kidney Diseases, and Organ Aging
This invention is a novel compound that can be used as a treatment for Acute Kidney Injury (AKI). This new method utilizes a small molecule agonist, capable of increasing mitochondrial biogenesis, which helps restore mitochondrial homeostasis and improves renal function and recovery. The compound showed beneficial effect in mouse model experiments.
Background:...
Published: 8/5/2024
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Inventor(s): Rick Schnellmann, Paul Victor Santiago Raj
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Nephrology/Renal, Technology Classifications > Life Sciences > Small Molecules
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Therapeutic Nanoparticles for Renal Disease
University of Arizona researchers have developed a technology that uses biodegradable, polymeric nanoparticles to specifically deliver drugs to the kidney, thereby bypassing off target/organ effects. For example, drugs such as formoterol, a beta 2 adrenergic agonist, can be used to treat acute and chronic renal disease. Encapsulation of these drugs...
Published: 12/15/2023
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Inventor(s): Rick Schnellmann, Heidi Mansour, David Encinas Basurto, Ernest Vallorz
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Drug Delivery
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Synthesis and Characterization of Innovative Formulations of Suramin Hydrogels for Drug Delivery and Applications Therein
This invention consists of new advanced formulations of the drug Suramin for administration by multiple routes. In addition, the invention surrounds the process and manufacturing of these newly formulated Suramin microparticles and nanoparticles so they can be effectively used in the treatment of wounds. Specifically, these new formulations would be...
Published: 11/16/2023
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Inventor(s): Heidi Mansour, Rick Schnellmann, David Encinas Basurto
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences > Therapeutics
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Advanced Engineered Formulations of Suramin Microparticles and Nanoparticles for Drug Delivery and Applications Therein
This invention consists of new advanced formulations of the drug Suramin for administration by multiple routes. In addition, the invention surrounds the process and manufacturing of these newly formulated Suramin microparticles and nanoparticles so they can be effectively used in the treatment of wounds. Specifically, these new formulations would be...
Published: 11/16/2023
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Inventor(s): Heidi Mansour, Rick Schnellmann, Maria Acosta
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Radiology, Technology Classifications > Life Sciences > Drug Delivery
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