PNA5 Treatment in Myocardial Ischemic Reperfusion Injury Decreases Infarction Size and Promotes Heart Function
This innovation is a novel method of treating cardiovascular disease, specifically, the continued tissue damage that occurs during myocardial ischemic reperfusion injury (MIRI) elicited by myocardial ischemia. While damage during MIRI is multifaceted, this new treatment addresses nearly every caveat including reactive oxygen species (ROS), calcium overload,...
Published: 4/4/2024
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Inventor(s): Meredith Hay, John Konhilas, Christina Hoyer-Kimura, Robin Polt
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Heart and Vascular
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A Device for Simultaneous Measurement of Pulmonary Ventilation and Metabolic Rate in Neonatal Rodents
University of Arizona researchers have developed a way of measuring and studying neonatal rodents' breathing activity and metabolic rate simultaneously using this homemade dual chamber technology. This inexpensive and simple tool is also useful for comparing the ventilatory and metabolic responses to various stressors, including hypoxia, acute inflammatory...
Published: 4/3/2023
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Inventor(s): Ralph Fregosi, Christina Hoyer-Kimura
Keywords(s):
Category(s): Technology Classifications > Research Tools
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Biomarker for Patient Stratification for Treatment of Cognitive Impairment in Patients with Vascular Contributions to Cognitive Impairment
This technology has found a serum biomarker that is efficacious in stratifying patients with vascular contributions to cognitive impairment and dementia (VCID) and Alzheimer’s disease related dementias (ADRD). This biomarker was able to indicate patients with high levels of VCID that are well suited for treatment with angiotensin peptides.
Background:
Worldwide,...
Published: 11/16/2023
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Inventor(s): Meredith Hay, John Konhilas, Christina Hoyer-Kimura, Thomas Beach, Geidy Serrano, Eric Reiman
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
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