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PNA5 Treatment in Myocardial Ischemic Reperfusion Injury Decreases Infarction Size and Promotes Heart Function

This innovation is a novel method of treating cardiovascular disease, specifically, the continued tissue damage that occurs during myocardial ischemic reperfusion injury (MIRI) elicited by myocardial ischemia. While damage during MIRI is multifaceted, this new treatment addresses nearly every caveat including reactive oxygen species (ROS), calcium overload,...

Published: 4/4/2024 | Inventor(s): Meredith Hay, John Konhilas, Christina Hoyer-Kimura, Robin Polt

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Category(s): Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Heart and Vascular

Biomarker for Patient Stratification for Treatment of Cognitive Impairment in Patients with Vascular Contributions to Cognitive Impairment

This technology has found a serum biomarker that is efficacious in stratifying patients with vascular contributions to cognitive impairment and dementia (VCID) and Alzheimer’s disease related dementias (ADRD). This biomarker was able to indicate patients with high levels of VCID that are well suited for treatment with angiotensin peptides. Background: Worldwide,...

Published: 11/16/2023 | Inventor(s): Meredith Hay, John Konhilas, Christina Hoyer-Kimura, Thomas Beach, Geidy Serrano, Eric Reiman

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics