|
CC16-Derived Analogs for the Treatment of Inflammatory and Obstructive Lung Diseases
This innovation relates to analogs/mimetics of CC16 also known as Urinary protein 1 (UPI), or Clara cell protein, or club cell protein. This protein is targeted for the treatment of cancer, chronic obstructive pulmonary disease, asthma, cystic fibrosis and any other diseases that CC16 may have activity in. The inventors have discovered a novel site...
Published: 6/10/2024
|
Inventor(s): Julie Ledford, Josef Vagner, Stefano Guerra, Michael Johnson
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary
|
|
Compositions for Treating and Preventing Lung Disease
This invention is a novel pharmaceutical composition for supplemental expression of a protein for the treatment of asthma and other pulmonary diseases. This method utilizes a surfactant protein, delivered via aerosolization to offer a more effective treatment option.
Background:
Asthma medicines of the 1940’s and 1950’s consisted of epinephrine...
Published: 11/20/2024
|
Inventor(s): Julie Ledford, Monica Kraft, Josef Vagner
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
|
|
Coronavirus Therapeutics
This technology introduces a potent covalent enzyme inhibitor designed specifically for targeting the cysteine protease, PLpro, a key player in the replication process of SARS coronaviruses like SARS-CoV-2 and MERS. Unlike traditional small molecule inhibitors, this inhibitor offers unparalleled efficacy and specificity, making it a promising candidate...
Published: 6/5/2024
|
Inventor(s): Rui Xiong, Gregory Thatcher, Divakar Indukuri, Kiira Ratia, Li jun Rong
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
|
|
Fluorinated Poly (β-Amino Ester) Nanoparticle for Highly Efficient and Specific Delivery of Nucleic Acids to the Lung Capillary Endothelium
This technology describes nanoparticles with specific structure design and modification for high efficiency and specific delivery of nucleic acids to the pulmonary endothelial cells. After intravenous administration, the nanoparticles were capable of delivering non-integrating DNA plasmids to lung microvascular endothelial cells but not to other lung...
Published: 2/6/2024
|
Inventor(s): Zicheng Deng, Vladimir Kalinichenko, Donglu Shi
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Drug Delivery
|
|
Mini-Sensor Suspension System for Supine CO2 Monitoring
University of Arizona researchers have developed a non-invasive device that measures carbon dioxide (CO2) concentration around a person’s face, which has important implications for patients in hospitals and treatment centers. By collecting and analyzing the respiratory gases around a supine subject’s face, the system can provide insights...
Published: 1/3/2024
|
Inventor(s): Yijie Chen, Md Tariqul Islam, Young-Jun Son, Esther Sternberg, Christopher Morton
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Medical Devices
|
|
Covid-19 Time of Intubation Mortality Evaluation (C-TIME)
This invention describes software that uses a scoring system for calculating the probable mortality of patients with COVID-19 pneumonia at the time they require mechanical ventilation.
Background:
Worldwide there have been over 208 million cases of severe acute respiratory coronavirus 2 (SARS-CoV-2) and over 4.37 million of these cases resulted in...
Published: 5/10/2023
|
Inventor(s): Craig Heise, Robert A. Raschke, Pooja Rangan, Sumit Agarwal, Suresh Uppalapu, Nehan Sher
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Healthcare Portfolios > Emergency Medicine
|
|
Method, System and Devices for Defining Respiratory Status
This invention is a system comprising FDA-approved MC10 BioStamp wearable sensors to gauge respiratory health in patients. The sensors are applied directly to the skin and can be used to produce gyroscopic data, including information around muscle activation and sleep. The data can be cross-referenced with observations from a motion capture system....
Published: 6/28/2023
|
Inventor(s): Marvin Slepian
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary
|
|
Virtual Reality Simulation for Airway Management
This invention is a dual haptic-virtual reality task training system for medical students and/or professionals learning tracheal tube intubation. This technology combines the current training method and a mannequin with VR/AR and a haptic feedback and force measuring system. By creating a medical training system with a more life-like simulation, users...
Published: 7/30/2024
|
Inventor(s): Jarrod Mosier, Young-Jun Son, David Biffar, Vignesh Subbian, Saurabh Jain, Bijoy Dripta Barua Chowdhury, Thomas Cahir, Eze Ahanonu
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Ear, Nose, & Throat, Technology Classifications > Healthcare Portfolios > Health Education, Medical Training and Operations, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Imaging & Optics > Medical Imaging
|
|
Innovative Approaches to Optimize the Therapeutic Benefit of Autophagy Inhibition
This invention is a set of novel synthetic compounds that demonstrate autophagy-inhibiting efficacy, useful for cancer and pulmonary hypertension treatment.
Background:
Autophagy is an evolutionarily conserved lysosomal protein degradation process. Aberrant autophagy plays a role in the pathogenesis of many health conditions including cancer, pulmonary...
Published: 4/3/2023
|
Inventor(s): Jennifer Carew, Steffan Nawrocki, Wei Wang
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Therapeutics
|
|
A New Device to Treat Pulmonary Arterial Hypertension (PAH) Through Neuromodulation
This invention is a method of treating pulmonary arterial hypertension without the use of drugs. The invention describes a system for bilateral electrical stimulation of the vagus nerve that can be implanted in the human body with the goal of ameliorating symptoms of pulmonary arterial hypertension. This device can be used with neonatal populations,...
Published: 4/3/2023
|
Inventor(s): Mohamed Ahmed, Philipp Gutruf
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Medical Devices > Therapeutic
|
