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Novel molecular design extends the reach of iron chelators to applications in cancer chemotherapy. This invention not only recognizes the higher demand of iron that characterizes cancer cells, but also takes into account other physiological differences between malignant cells and the surrounding tissue. Specifically, pro-drugs are designed to activate...

Published: 3/12/2024 | Inventor(s): Elisa Tomat, Eman Akam, Yu-Shien Sung

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Category(s): Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Blood & Lymphatic Disease, Technology Classifications > Healthcare Portfolios > Oncology

Beta-Adrenergic Receptor Activation to Increase the Potency and Safety of Peripheral Blood Stem Cell Grafts

This technology features a method for altering immune cell composition of peripheral blood stem cell grafts in donors or patients prior to collection and transplantation to treat blood and immune deficiency diseases. The technology aims to alter immune cell subtypes in the graft to evoke increased graft-versus-tumor effects and reduce the incidence...

Published: 4/3/2023 | Inventor(s): Richard Simpson, Emmanuel Katsanis, Richard Bond

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Blood & Lymphatic Disease, Technology Classifications > Healthcare Portfolios > Transplantation