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Isolation and Separation of Angiotensin I and II from Human Serum Using a New Chromatographic Matrix that Excludes High Molecular Weight Proteins
This innovation introduces a novel chromatographic matrix that effectively isolates and separates angiotensin I and II, key biomarkers involved in blood pressure regulation, from human serum. The system uses a hybrid combination matrix that selectively removes small molecular weight polypeptides while excluding large serum proteins. By integrating chelating...
Published: 1/6/2026
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Inventor(s): Roberto Guzman, David Mier-Salazar, Daniel Alejandro Diaz
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Blood & Lymphatic Disease, Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic
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Analytical Technology for the Isolation of 3-Nitrotyrosine as a Biomarker from Urine to Assess Depression and Acute Kidney Injury
This invention uses a novel separation technique to isolate specific biomarkers from urine, as a measure to detect and monitor depression and acute kidney injury (AKI). The system employs a hybrid chromatographic matrix that rejects biomolecules of specific sizes and allows only the desired small compounds, such as 3-nitrotyrosine (which has been linked...
Published: 1/6/2026
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Inventor(s): Roberto Guzman, David Mier-Salazar
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Nephrology/Renal, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic
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A Flexible, Scalable Platform Technology to Augment Antibiotic Efficacy
This invention relates to a novel, safe, and efficacious approach to reduce antibiotic concentrations required to kill pathogenic bacteria. The product thus augments antibiotic efficacy, including against bacteria that are clinically resistant.
Background:
One of the biggest risks to global public health is antibiotic resistance. Through processes...
Published: 12/1/2025
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Inventor(s): Gayatri Vedantam, Virinchipuram Viswanathan, Arun Sharma, David Stewart
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics
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Isolation of Protein Biomarkers from Saliva as a Technology to Assess and Monitor Cardiac Infarction
This technology introduces a novel separation method designed to isolate small protein biomarkers directly from saliva, enabling a rapid and non-invasive diagnostic approach for cardiac infarction. The system employs a hybrid chromatographic matrix that selectively rejects large proteins while allowing smaller biomarkers to interact with affinity sites...
Published: 11/24/2025
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Inventor(s): Roberto Guzman, David Mier-Salazar, Christopher Rodriguez
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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A Precision Anti-Infective for Enterococcus sp Eradication as well as Selective Decontamination
This innovation is a water-soluble nanocarrier that can precisely and quickly eradicate the healthcare-associated pathogen enterococci. The carrier can complex with oligonucleotides that can bind to bacterial mRNA, preventing translation and inhibiting bacterial functions of enterococci. It is also non-toxic to both human tissue and bacteria and may...
Published: 10/20/2025
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Inventor(s): Gayatri Vedantam, Virinchipuram Viswanathan, Arun Sharma, David Stewart
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
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Interferometric Focal Planes
This technology introduces a new kind of camera sensor in which each pixel functions as a tiny interferometer, instead of a standard light detector. This allows the sensor to capture not only the brightness of a scene but also additional information about the light’s spatial coherence. By leveraging arrays of integrated interferometers, the system...
Published: 9/29/2025
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Inventor(s): David Brady, Shengtai Zhu, Zhipeng Dong
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Lens & System Design
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Visualizing the Impact of Changes in Microservices
This technology is a Software Architecture Visualization and Analysis Tool (SAVAT) designed to assist developers in understanding the impacts and ripple effects of changes in microservice systems. This SAVAT generates visualizations of microservice interactions in the system from service and domain architectural views, integrating context maps, service...
Published: 9/12/2025
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Inventor(s): Tomas Cerny, Gabriel Goulis, Adam Rahmani, David Kozak, Tomas Vojnar
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Communications & Networking
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A Novel Biomimetic Method of Biosensor and Electronics Adhesion in the Musculoskeletal System
This technology introduces a novel, biomimetic method securely attaching biosensors and bioelectronics to musculoskeletal tissues. By mimicking natural adhesive processes found in marine organisms, it enables durable, long-term bonding between sensors coated with Parylene C and various tissues such as bone, cartilage, muscle, and tendon, and a stable...
Published: 8/11/2025
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Inventor(s): David Margolis, Gerardo Figueroa Romero
Keywords(s):
Category(s): Technology Classifications > Sensors & Controls, Technology Classifications > Sensors & Controls > Biologic, Technology Classifications > Materials > Biocompatible, Technology Classifications > Healthcare Portfolios > Musculoskeletal Disorders, Orthopedics/Bone
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Snapshot Wavefront Camera
This invention is a reference-free snapshot wavefront camera that can be used to measure both amplitude and phase of the wavefront. The camera uses a two-dimensional diffraction grating to split the incoming wavefront into multiple copies which then travel through a lens that focuses them onto a sensor in a camera array. The resulting wavefront information...
Published: 7/2/2025
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Inventor(s): David Brady, Ni Chen, Shengtai Zhu, Gregory Nero
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Imaging & Optics > Ophthalmology
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Integrated Photonic Encoding Systems and Methods for High Speed and Low Power Image Processing
The photonic processing system described in this invention is able to perform large-scale matrix multiplication in an energy-efficient manner with the encoding matrix being designed such that encoded data can be decoded with high-fidelity for post-processing, such as reconstructing compressed images and image conditioning applications.
In addition,...
Published: 7/2/2025
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Inventor(s): David Brady
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Imaging & Optics > Data Storage, Technology Classifications > Imaging & Optics > Materials & Fabrication > Optical, EO & MO
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