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Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels
This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...
Published: 3/23/2026
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Updated: 3/23/2026
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Inventor(s): Alex McGhee, Kelvin Pond, A Departmental Work
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays
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Fenotyper
Fenotyper is an artificial intelligence (AI) based software platform that generates clinical phenotype definitions from plain-language descriptions, leveraging Large Language Models (LLM) and Retrieval-Augmented Generation (RAG). The system converts a researcher’s or clinician’s description of a patient population of interest into a structured...
Published: 3/23/2026
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Updated: 3/23/2026
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Inventor(s): Vignesh Subbian, Yehonathan Kleinerman, David Maughan
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology
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Amine-Based Glycolipid Polymeric Media
This invention is a family of reusable hybrid polymer materials, made as hydrogels or resin-like beads, designed to remove dissolved metals from water. The materials are built from glycolipid-based building blocks that are modified with metal binding groups, then formed into stable gels, beads, coatings, or thin films. In use, the media is placed in...
Published: 3/23/2026
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Updated: 3/23/2026
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Inventor(s): David Hogan, Nanayakkarawasan Pallage Nanayakkara, Raina Maier, Douglas Loy
Keywords(s):
Category(s): Technology Classifications > Energy, Cleantech & Environmental > Remediation > Soil, Technology Classifications > Energy, Cleantech & Environmental > Remediation > Water, Technology Classifications > Materials > Polymers
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Fusarivir: a Bacterial Delivery Mechanism to Insert Mycoviruses into Fusarium Oxysporum
This invention is a platform for delivering mycoviruses—viruses that infect fungi—directly into fungal cells using engineered bacteria. Due to the absence of a protein shell, mycoviruses require a delivery mechanism to enter fungal cells and suppress host pathogenicity. This method utilizes an intrahyphal bacterium, which enters fungal hyphae...
Published: 2/9/2026
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Updated: 2/9/2026
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Inventor(s): Moshe Steyn, David Baltrus
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture > Plant Pathogens
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Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 2/9/2026
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Updated: 2/9/2026
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Inventor(s): A Departmental Work, Michael Brown
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools
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Isolation and Separation of Angiotensin I and II from Human Serum Using a New Chromatographic Matrix that Excludes High Molecular Weight Proteins
This innovation introduces a novel chromatographic matrix that effectively isolates and separates angiotensin I and II, key biomarkers involved in blood pressure regulation, from human serum. The system uses a hybrid combination matrix that selectively removes small molecular weight polypeptides while excluding large serum proteins. By integrating chelating...
Published: 1/6/2026
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Updated: 1/6/2026
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Inventor(s): Roberto Guzman, David Mier-Salazar, Daniel Alejandro Diaz
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Blood & Lymphatic Disease, Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic
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Analytical Technology for the Isolation of 3-Nitrotyrosine as a Biomarker from Urine to Assess Depression and Acute Kidney Injury
This invention uses a novel separation technique to isolate specific biomarkers from urine, as a measure to detect and monitor depression and acute kidney injury (AKI). The system employs a hybrid chromatographic matrix that rejects biomolecules of specific sizes and allows only the desired small compounds, such as 3-nitrotyrosine (which has been linked...
Published: 1/6/2026
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Updated: 1/6/2026
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Inventor(s): Roberto Guzman, David Mier-Salazar
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Nephrology/Renal, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic
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A Flexible, Scalable Platform Technology to Augment Antibiotic Efficacy
This invention relates to a novel, safe, and efficacious approach to reduce antibiotic concentrations required to kill pathogenic bacteria. The product thus augments antibiotic efficacy, including against bacteria that are clinically resistant.
Background:
One of the biggest risks to global public health is antibiotic resistance. Through processes...
Published: 3/12/2026
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Updated: 12/1/2025
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Inventor(s): Gayatri Vedantam, Virinchipuram Viswanathan, Arun Sharma, David Stewart
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics
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Isolation of Protein Biomarkers from Saliva as a Technology to Assess and Monitor Cardiac Infarction
This technology introduces a novel separation method designed to isolate small protein biomarkers directly from saliva, enabling a rapid and non-invasive diagnostic approach for cardiac infarction. The system employs a hybrid chromatographic matrix that selectively rejects large proteins while allowing smaller biomarkers to interact with affinity sites...
Published: 11/24/2025
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Updated: 11/24/2025
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Inventor(s): Roberto Guzman, David Mier-Salazar, Christopher Rodriguez
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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A Precision Anti-Infective for Enterococcus sp Eradication as well as Selective Decontamination
This innovation is a water-soluble nanocarrier that can precisely and quickly eradicate the healthcare-associated pathogen enterococci. The carrier can complex with oligonucleotides that can bind to bacterial mRNA, preventing translation and inhibiting bacterial functions of enterococci. It is also non-toxic to both human tissue and bacteria and may...
Published: 3/12/2026
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Updated: 10/20/2025
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Inventor(s): Gayatri Vedantam, Virinchipuram Viswanathan, Arun Sharma, David Stewart
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
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