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A Flexible, Scalable Platform Technology to Augment Antibiotic Efficacy
This invention relates to a novel, safe, and efficacious approach to reduce antibiotic concentrations required to kill pathogenic bacteria. The product thus augments antibiotic efficacy, including against bacteria that are clinically resistant.
Background:
One of the biggest risks to global public health is antibiotic resistance. Through processes...
Published: 12/1/2025
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Inventor(s): Gayatri Vedantam, Virinchipuram Viswanathan, Arun Sharma, David Stewart
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics
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Isolation of Protein Biomarkers from Saliva as a Technology to Assess and Monitor Cardiac Infarction
This technology introduces a novel separation method designed to isolate small protein biomarkers directly from saliva, enabling a rapid and non-invasive diagnostic approach for cardiac infarction. The system employs a hybrid chromatographic matrix that selectively rejects large proteins while allowing smaller biomarkers to interact with affinity sites...
Published: 11/24/2025
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Inventor(s): Roberto Guzman, David Mier-Salazar, Christopher Rodriguez
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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A Precision Anti-Infective for Enterococcus sp Eradication as well as Selective Decontamination
This innovation is a water-soluble nanocarrier that can precisely and quickly eradicate the healthcare-associated pathogen enterococci. The carrier can complex with oligonucleotides that can bind to bacterial mRNA, preventing translation and inhibiting bacterial functions of enterococci. It is also non-toxic to both human tissue and bacteria and may...
Published: 10/20/2025
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Inventor(s): Gayatri Vedantam, Virinchipuram Viswanathan, Arun Sharma, David Stewart
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
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Interferometric Focal Planes
This technology introduces a new kind of camera sensor in which each pixel functions as a tiny interferometer, instead of a standard light detector. This allows the sensor to capture not only the brightness of a scene but also additional information about the light’s spatial coherence. By leveraging arrays of integrated interferometers, the system...
Published: 9/29/2025
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Inventor(s): David Brady, Shengtai Zhu, Zhipeng Dong
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Lens & System Design
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Visualizing the Impact of Changes in Microservices
This technology is a Software Architecture Visualization and Analysis Tool (SAVAT) designed to assist developers in understanding the impacts and ripple effects of changes in microservice systems. This SAVAT generates visualizations of microservice interactions in the system from service and domain architectural views, integrating context maps, service...
Published: 9/12/2025
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Inventor(s): Tomas Cerny, Gabriel Goulis, Adam Rahmani, David Kozak, Tomas Vojnar
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Communications & Networking
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A Novel Biomimetic Method of Biosensor and Electronics Adhesion in the Musculoskeletal System
This technology introduces a novel, biomimetic method securely attaching biosensors and bioelectronics to musculoskeletal tissues. By mimicking natural adhesive processes found in marine organisms, it enables durable, long-term bonding between sensors coated with Parylene C and various tissues such as bone, cartilage, muscle, and tendon, and a stable...
Published: 8/11/2025
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Inventor(s): David Margolis, Gerardo Figueroa Romero
Keywords(s):
Category(s): Technology Classifications > Sensors & Controls, Technology Classifications > Sensors & Controls > Biologic, Technology Classifications > Materials > Biocompatible, Technology Classifications > Healthcare Portfolios > Musculoskeletal Disorders, Orthopedics/Bone
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Snapshot Wavefront Camera
This invention is a reference-free snapshot wavefront camera that can be used to measure both amplitude and phase of the wavefront. The camera uses a two-dimensional diffraction grating to split the incoming wavefront into multiple copies which then travel through a lens that focuses them onto a sensor in a camera array. The resulting wavefront information...
Published: 7/2/2025
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Inventor(s): David Brady, Ni Chen, Shengtai Zhu, Gregory Nero
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Imaging & Optics > Ophthalmology
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Integrated Photonic Encoding Systems and Methods for High Speed and Low Power Image Processing
The photonic processing system described in this invention is able to perform large-scale matrix multiplication in an energy-efficient manner with the encoding matrix being designed such that encoded data can be decoded with high-fidelity for post-processing, such as reconstructing compressed images and image conditioning applications.
In addition,...
Published: 7/2/2025
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Inventor(s): David Brady
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Imaging & Optics > Data Storage, Technology Classifications > Imaging & Optics > Materials & Fabrication > Optical, EO & MO
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Treadmill with Soft Ambulatory Surfaces
This invention is a specialized treadmill to study rat gait and mobility on simulated extraterrestrial terrains. This treadmill uses various harness-based gravity simulators and sensors for real-time physiological data collection. It can be used on a variety of ambulatory surfaces and used for many different applications.
Background:
Currently,...
Published: 7/22/2025
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Inventor(s): David Margolis, Philipp Gutruf, Gerardo Figueroa Romero, Kevin Kasper, Gabriel Vogt, Avery Miller, Alicia Enriquez, Juan Campista, Will Stephenson, Alexis Barber
Keywords(s):
Category(s): Technology Classifications > Research Tools
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Graph Theory Based Least Squares Optimization Algorithm for Behavioral Estimation (G.L.O.B.E.)
This is an advanced software tool that analyzes functional neuroimaging data to map brain oscillations and predict optimal task timing across cognitive domains. By integrating MRI-based connectivity data with user input, it provides insight into the understanding of how different brain states interact. This predictive software intends to provide recommendations...
Published: 7/22/2025
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Inventor(s): David Negelspach, William Killgore
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Education & Training
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