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Fifth Harmonic and Five-Photon Excitation Fluorescence Multiphoton Microscopy
This technology introduces a fifth-order multiphoton microscopy system. This advanced method enables high-resolution, label-free imaging of biological samples using nonlinear optical effects. Laser scanning multiphoton microscopy has gained prevalence across a wide range of applications due to its high-resolution imaging potential. This system uses...
Published: 6/23/2025
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Inventor(s): Khanh Kieu
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection > Inspection, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry, Technology Classifications > Engineering & Physical Sciences > Semiconductors, Technology Classifications > Research Tools
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Treadmill with Soft Ambulatory Surfaces
This invention is a specialized treadmill to study rat gait and mobility on simulated extraterrestrial terrains. This treadmill uses various harness-based gravity simulators and sensors for real-time physiological data collection. It can be used on a variety of ambulatory surfaces and used for many different applications.
Background:
Currently,...
Published: 6/9/2025
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Inventor(s): David Margolis, Philipp Gutruf, Gerardo Figueroa Romero, Kevin Kasper, Gabriel Vogt, Avery Miller, Alicia Enriquez, Juan Campista, Will Stephenson, Alexis Barber
Keywords(s):
Category(s): Technology Classifications > Research Tools
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Predictive mRNA Biomarker for Progressive Coccidioidomycosis When Infected
This invention introduces a blood-based diagnostic test to assess coccidioidomycosis progression risk. The test is broken down into three overall steps: 1) blood collection, 2) ex vivo stimulation, and 3) mRNA quantification. This technology identified a predictive a gene set/biomarkers for coccidioidomycosis that was independently validated across...
Published: 5/19/2025
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Inventor(s): John Galgiani, Yves Lussier
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools
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AI-Assisted Computational Prediction of Protein Functionality
This invention centers on creating a database and algorithms to explore protein functionality and interactions. The aim is to enable significant scientific discoveries, novel drug targeting, and the engineering of synthetic receptors like chimeric antigen receptors (CARs). By studying proteins involved in T cell activation over 450 million years of...
Published: 4/17/2025
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Inventor(s): Michael Kuhns, Koenraad Van Doorslaer, Kevin Scott, Andrew Girvin
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Research Tools, Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation
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Incubator Microplate Rack
This invention is a specialized incubator rack system designed to optimize cell culture in microplates by providing uniform growth conditions (equal airflow, humidity, and thermal conditions) for all plates regardless of their position in the stack. This rack ensures consistent growth conditions for cells compared to traditional incubator practices...
Published: 3/5/2025
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Inventor(s): Matthew Kaplan
Keywords(s):
Category(s): Technology Classifications > Research Tools, Technology Classifications > Life Sciences
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Colorectal Cancer Prognostic/Prediction
This technology provides a gene score system to assess the effectiveness of antifibrotic treatments on colorectal cancer (CRC). By comparing gene expressions from colorectal cancer cells under two different types of mechanical conditioning, this system identifies specific gene signatures that correlate with an increased risk of metastasis and lower...
Published: 4/1/2025
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Inventor(s): Ghassan Mouneimne
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools
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Platform Development to Improve Bar Data Tracking, Analysis, and Reporting
This technology offers a modern solution for law schools to efficiently track and analyze bar exam performance data. This platform simplifies this process by enabling more sophisticated data management and analysis, allowing schools to identify key predictors of bar exam success and implement targeted study interventions. By leveraging this platform,...
Published: 1/17/2025
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Inventor(s): Jessica Findley, Michael Wagenheim
Keywords(s):
Category(s): Technology Classifications > Research Tools, Technology Classifications > Software & Information Technology > Education & Training
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Time Resolved Fluorescence based HTS to Detect Structural Changes in cTnI
This innovation involves the development of a probe that attaches to a specific protein called cardiac troponin I (cTnI), which is involved in muscle contraction of the heart. This probe, created through genetic engineering techniques, is designed to detect changes in cTnI's neighboring protein, cardiac troponin T (cTnT). When there's a change...
Published: 5/13/2024
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Inventor(s): Romi Castillo, Jil Tardiff
Keywords(s):
Category(s): Technology Classifications > Research Tools, Technology Classifications > Sensors & Controls > Biologic, Technology Classifications > Life Sciences > Biologics, Technology Classifications > Healthcare Portfolios > Heart and Vascular
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A Dual-Luciferase Reporter System for Characterization of Small RNA Target Genes in both Mammalian and Insect Cells
MicroRNAs (miRNAs) are regulatory RNA molecules that bind to target messenger RNAs (mRNAs) and affect the stability or translational efficiency of the bound mRNAs. Single or dual-luciferase reporter systems have been successfully used to identify miRNA target genes in mammalian cells, however, they are not sensitive enough to verify miRNA–target...
Published: 5/7/2024
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Inventor(s): Xianchun Li
Keywords(s):
Category(s): Technology Classifications > Research Tools > Reagents, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Screening assays
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Chemistry by Design
Title: Chemistry by DesignInvention: This invention is a custom database of worldwide approved pharmaceutical structures, including the United States FDA, that are available for use via a commercial app.Background: Any substance, or mixture of substances, that is planned to be an active ingredient for a drug product is classified as an active pharmaceutical...
Published: 3/12/2024
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Inventor(s): Jon Njardarson
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Software & Information Technology > Bioinformatics, Technology Classifications > Research Tools
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