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Interface Profilometry with Third Harmonic Generation Microscopy
This invention describes a method of third harmonic-generation (THG) multiphoton microscopy for interface profilometry with depth resolution at the nanometer scale. While the axial resolution of the system is on the scale of micrometers, this invention can precisely define the peak of a THG depth response curve, or how intensity varies as a function...
Published: 11/10/2025
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Inventor(s): Khanh Kieu
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Materials & Fabrication, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Sensors and Detection
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Fifth Harmonic and Five-Photon Excitation Fluorescence Multiphoton Microscopy
This technology introduces a fifth-order multiphoton microscopy system. This advanced method enables high-resolution, label-free imaging of biological samples using nonlinear optical effects. Laser scanning multiphoton microscopy has gained prevalence across a wide range of applications due to its high-resolution imaging potential. This system uses...
Published: 6/23/2025
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Inventor(s): Khanh Kieu
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection > Inspection, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry, Technology Classifications > Engineering & Physical Sciences > Semiconductors, Technology Classifications > Research Tools
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All-Fiber Single-Cavity Dual-Comb for Coherent Anti-Stokes Raman Scattering Spectroscopy based on Spectral Focusing
This technology is an an all-fiber, single-cavity, free-running, dual-comb laser system based on spectral focusing. This technique can be used in coherent anti-Stokes Raman scattering spectroscopy (CARS) and label free imaging for a variety of applications.
Background:
CARS is a form of spectroscopy used primarily in chemistry, physics, and related...
Published: 7/26/2024
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Inventor(s): Khanh Kieu, Yukun Qin
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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Bidirectional Mode-locked Fiber Laser for Dual Comb Spectroscopy
Researchers at the University of Arizona have developed a free-running bidirectional mode-locked fiber laser operating at telecommunications wavelengths. Two coherent femtosecond frequency combs are generated from a single laser cavity to ensure mutual coherent properties and common noise cancellation.
Background:
Optical frequency combs (OFCs) are...
Published: 4/3/2023
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Inventor(s): Khanh Kieu
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Lasers & Other Sources, Technology Classifications > Imaging & Optics > Fiber Optics, Technology Classifications > Engineering & Physical Sciences > Photonics
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SHG Imaging Technique for Assessing Hybrid EO Polymer/Silicon Photonic Integrated Circuits
Scientists at the University of Arizona have developed a system for assessing the efficiency of the electro-optic (EO) polymer poling process by using multi-photon imaging in the second harmonic generation mode (SHG), permitting imaging and assessment of waveguide devices, including poled polymer devices, prior to, during, and after fabrication. This...
Published: 4/3/2023
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Inventor(s): Robert Norwood, Khanh Kieu, Roland Himmelhuber
Keywords(s): electro-optic polymer, hybrid photonic integrated circuits, SHG imaging, silicon photonics
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Imaging & Optics > Sensors and Detection > Inspection
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High Efficient Continuous Wave and Mode-Locked Lasers Powered by Solar Energy
Faculty at the University of Arizona have developed a compact, efficient solar-powered laser that uses triple junction photovoltaic cells to power semiconductor and mode-locked lasers. Existing solar-pumped lasers use an arc-metal-halide lamp pump that requires bulky concentrating optics and is power inefficient. By using a triple junction photovoltaic...
Published: 8/1/2024
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Inventor(s): Stanley Pau, Khanh Kieu, Stanley Johnson
Keywords(s): energy conversion, mode-locked laser, semiconductor laser, solar photovoltaic
Category(s): Technology Classifications > Engineering & Physical Sciences
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Fiber-Based Bidirectional Optical Parametric Oscillator for Precision Sensing
Researchers at the University of Arizona have developed an all-fiber, synchronously pumped, bidirectional optical parametric oscillator (OPO) for precision sensing applications. The all-fiber design removes the need for free-space alignment and adjustment. The design overcomes the limitations of existing laser gyros by increasing the sensing area for...
Published: 1/10/2024
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Inventor(s): Khanh Kieu
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection
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