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Antibody Therapy and Diagnosis for Microsporidiosis Disease in Shrimp Aquaculture
This invention is a therapy against Ecytonucleospora hepatopenaei (EHP) and diagnostic method to identify EHP-infected shrimp using monoclonal antibodies. The antibodies can be produced in cell culture or expressed using a heterologous expression system for administering to shrimp broodstock, post larvae in a hatchery, and in farmed shrimp in a grow...
Published: 10/18/2024
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Inventor(s): Arun Dhar, Michael Riggs, Deborah Schaefer
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture > Aquaculture, Technology Classifications > Veterinary Medicine > Therapeutics & Vaccines
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Shrimp Viral Promoters for Gene Expression and Uses Thereof
This is a novel promoter for gene expression that can be used across species. By understanding the genetic makeup of animals and insects, we can learn how to improve human life. Viruses that affect crustaceans may be able to provide insight into genetic promoters that can interact with prokaryotic and eukaryotic cells.
There are different types of...
Published: 7/23/2024
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Inventor(s): Arun Dhar, Nam Hung Mai
Keywords(s):
Category(s): Technology Classifications > Research Tools, Technology Classifications, Technology Classifications > Agriculture & Horticulture > Aquaculture
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Time-Resolved Fluorescence Measurements in Real-Time
A prototype instrument that uses fast switching photomultiplier tube (PMT) to acquire real-time time-resolved fluorescence lifetime data has been developed and tested at the University of Arizona. The PMT detector can collect fluorescence data at rates as high as 200 MHz without the production of switching transients. The circuit system also demonstrates...
Published: 4/3/2023
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Inventor(s): Linda Powers, Jerrie Fairbanks, Varun Sridharan, Xiang Zhang, Xavier Ramus, Andrew Duncan
Keywords(s): fluorescence, high NA, high speed data collection, real-time data collection, time-resolved data collection
Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics
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Viral Vector for Developing Oral Vaccines and Therapeutics Against Diseases in Aquatic Animals
This technology uses a genetically engineered replication deficient virus as a vector to deliver genes encoding vaccine (i.e. antigen) or therapeutic nucleic acid (e.g. RNAi molecules). The vaccine gene can be purified and used as an injectable vaccine in fin fish. In fin fish, the vaccine gene will express the antigen and immunize the vaccinated fish....
Published: 6/27/2024
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Inventor(s): Arun Dhar, Arjoneel Dhar, Rod Alenton
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture > Aquaculture, Technology Classifications > Life Sciences > Vaccines
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Rapid Diagnosis of Microbial Pathogens in Aquatic Species
This technology is a rapid colorimetric assay to detect and diagnose diseases in various aquaculture species by utilizing a loop-mediated isothermal amplification (LAMP) and reverse-transcription loop-mediated isothermal amplification-based (RT-LAMP) assay. This product allows sensitive detection of <100 viral, bacterial, and fungal pathogen genomes...
Published: 6/27/2023
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Inventor(s): Luis Aranguren Caro, Arun Dhar, Nam Hung Mai
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture > Aquaculture, Technology Classifications > Life Sciences > Diagnostics
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Genetic Markers For Resistance Against Acute Hepatopancreatic Necrosis Disease (AHPND) In Shrimp
This invention describes a genetic line resistant to Acute Hepatopancreatic Necrosis Disease (AHPND). A gene expression analyses was conducted to measure the relative expression of genes in two populations of shrimp (susceptible and resistant lines). Differentially expressed genes have been identified as markers for resistance and/or susceptibility...
Published: 4/3/2023
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Inventor(s): Nam Hung Mai, Arun Dhar, Luis Aranguren Caro
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture > Aquaculture
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Therapeutic and Prophylactic Measures of Acute Hepatopancreatic Necrosis Disease (AHPND) in Shrimp
Acute Hepatopancreatic Necrosis Disease (AHPND) also known as Early Mortality Syndrome (EMS) is one of the most devastating diseases for shrimp farming in the last decade. Since its discovery in 2009, AHPND caused $2.56 billion dollars worth of losses in Vietnam, $11.6 billion in Thailand, and significant losses worldwide as the disease increases its...
Published: 4/3/2023
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Inventor(s): Nam Hung Mai, Arun Dhar
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture > Aquaculture, Technology Classifications > Life Sciences > Therapeutics
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Acute Hepatopancreatic Necrosis Disease (AHPND) Control Using Plant-Derived Natural Extracts, and Thereof
This technology is an antimicrobial phytogenic supplement to therapeutically treat Acute Hepatopancreatic Necrosis Disease (AHPND) in shrimp. AHPND is caused by a Vibiro parahaemolyticus producing toxin and is a threat to sustainable shrimp farming globally. Plant-derived extract NE05 is effective at controlling AHPND and potentially other bacterial...
Published: 4/3/2023
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Inventor(s): Arun Dhar, Sukanniya Kaneshamoorthy, Nam Hung Mai, Sadhana Ravishankar
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture > Aquaculture
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Detection of EMS and EHP
This technology seeks to improve on conventional Polymerase Chain Reaction (PCR) testing methods for the shrimp aquaculture disease Acute Heptopancreatic Necrosis Disease (AHPND). This new approach is quantitative and targets plasmid toxins that are present in the bacteria that cause AHPND. While conventional AHPND diagnostic PCR kits base their identification...
Published: 4/3/2023
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Inventor(s): Siddhartha Kanrar, Arun Dhar
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture > Aquaculture
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New PCR and qPCR Methods For NHP Detection
This technology provides a more accurate test for detecting necrotizing hepatopancreatitis (NHP) bacteria (NHPB) in farmed shrimp. The development of these highly specific PCR and qPCR methods for detecting NHPB eliminate false positives and non-specific amplifications seen in current detection methods.
Background:
The worldwide shrimp farming industry...
Published: 4/3/2023
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Inventor(s): Luis Aranguren Caro, Arun Dhar, Roberto Cruz-Flores
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture > Aquaculture
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