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The Use of Cold Plasma to Facilitate CRISPR
This technology is a compact, automated cold plasma generator engineered to enable safe and efficient delivery of CRISPR-Cas9 into cells without chemical reagents. Through the use of cold plasma, cell membranes are transiently permeabilized, creating a controlled pathway for the entry of gene-editing components. This approach directly addresses critical...
Published: 10/9/2025
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Inventor(s): Sara Sheikhlary
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences > Therapeutics
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Methods to Differentiate Naive and Pluripotent Stem Cell-Derived B Cells into Plasma Cells
This invention is a method to generate plasma cells from primary and stem cell-derived B cells and includes characterization of cellular intermediates during the maturation process.
Background:
The inefficient generation of plasma cells from primary naïve B cells is due to a combination of intrinsic cellular limitations and external signaling...
Published: 9/22/2025
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Inventor(s): Deepta Bhattacharya, Colin Fields
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences > Stem Cells, Technology Classifications > Research Tools > Cell Lines
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Dual-Functional Tetrazine Reagents for Bis-Thiol Bioconjugation and Functionalization
This method is for a novel dual-functional tetrazine reagent with application in Cys-specific bioconjugation and functionalization of target proteins. This class of compounds can be utilized for specific bis-thiol targeting.
Background:
Bioconjugates are molecules with altered chemical structures via substrates or reagents that allows for biomolecule...
Published: 2/18/2025
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Inventor(s): Wei Wang
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Healthcare Portfolios, Technology Classifications > Research Tools > Reagents
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Dual Performing Vinyl-tetrazine for Rapid, Selective Bioconjugation and Functionalization of Cysteine Proteins
This method is for a novel dual-functional tetrazine reagent with application in Cys-specific bioconjugation and functionalization of target proteins. This class of compounds can be utilized for specific single-thiol targeting. This novel method possesses an electron withdrawing tetrazine substituted vinyl moiety that exists as a Michael receptor for...
Published: 2/17/2025
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Inventor(s): Wei Wang
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Healthcare Portfolios, Technology Classifications > Research Tools > Reagents
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Multi-Modality Machine Learning for Pain Outcomes
Chronic pain affects millions of people, making it a challenging condition to effectively manage. Traditional methods of assessing and treating pain rely heavily on subjective measures, which can lack accuracy and sensitivity. As a result, there is a growing need for objective tools to assess chronic pain and improve treatment outcomes. EEG (electroencephalography)...
Published: 12/16/2024
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Inventor(s): Julie Pilitsis, Ilknur Telkes
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Software & Information Technology > Health IT
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3D Rendering and Endoscope Tracking Software for Virtual Reality Surgical Training System with Haptic Feedback
This invention provides medical students and professionals the ability to practice surgical techniques in virtual reality with true haptic feedback. This technology is currently designed for otolaryngology procedures where users are provided with a virtual reality headset and imitation medical tools for operating on a tangible model head.
Background:...
Published: 11/9/2024
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Inventor(s): Saurabh Jain, Young-Jun Son, Eugene Chang, Samuel Barber
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Medical Devices, Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Software & Information Technology > Education & Training
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Room Scale Virtual/Hybrid Reality Endoscopic Surgery Simulation System Using and Synchronized Patient-Specific Anatomy Virtual and Physical Models
This invention provides medical students and professionals the ability to practice surgical techniques in virtual reality with true haptic feedback. This technology is currently designed for otolaryngology procedures where users are provided with a virtual reality headset and imitation medical tools for operating on a tangible model head.
Background:...
Published: 11/9/2024
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Inventor(s): Samuel Barber, Saurabh Jain, Young-Jun Son, Eugene Chang
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Medical Devices, Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Software & Information Technology > Education & Training
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Endoscope With Haptic Feedback and VR Controllers for Virtual Reality Surgical Training System
This invention provides medical students and professionals the ability to practice surgical techniques in virtual reality with true haptic feedback. This technology is currently designed for otolaryngology procedures where users are provided with a virtual reality headset and imitation medical tools for operating on a tangible model head.
Background:...
Published: 11/9/2024
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Inventor(s): Samuel Barber, Saurabh Jain, Young-Jun Son, Eugene Chang
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Education & Training, Technology Classifications > Healthcare Portfolios, Technology Classifications > Medical Devices, Technology Classifications > Research Tools > Simulators and Modeling Tools
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Container Therapeutics at Point of Care
This technology is an innovative method and system for streamlining the production of therapeutic delivery systems. Central to this innovation is the integration of various stages of production, from raw material collection to final product delivery, within a mobile infrastructure. A key embodiment involves the utilization of a container-like structure...
Published: 6/24/2024
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Inventor(s): Frederic Zenhausern
Keywords(s):
Category(s): Technology Classifications > Agriculture & Horticulture, Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics
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Wearable Wireless Power Supply and Data Communication Device for Small Battery Free Implant
This is a Near-Field Communication (NFC) enabled technology that can be embedded in wearable materials to charge battery-free implants. It allows for the implants to be charged by power casters from a distance, meaning they remain fully operational 24 hours a day, 7 days a week, for months on end. It will also reduce the space a battery on an implantable...
Published: 8/1/2024
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Inventor(s): Philipp Gutruf, Tucker Stuart, Kevin Kasper
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Communications & Networking, Technology Classifications > Engineering & Physical Sciences, Technology Classifications > Healthcare Portfolios
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