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Methods to Differentiate Naive and Pluripotent Stem Cell-Derived B Cells into Plasma Cells
This invention is a method to generate plasma cells from primary and stem cell-derived B cells and includes characterization of cellular intermediates during the maturation process.
Background:
The inefficient generation of plasma cells from primary naïve B cells is due to a combination of intrinsic cellular limitations and external signaling...
Published: 9/22/2025
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Inventor(s): Deepta Bhattacharya, Colin Fields
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences > Stem Cells, Technology Classifications > Research Tools > Cell Lines
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Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023
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Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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All-Fiber Multicore Fiber Laser Devices
Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...
Published: 4/3/2023
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Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Fiber Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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