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Novel, Humanized Transgenic Background Mouse Strain for Neurodegenerative Disease Research
This invention is a transgenic mouse model for the study of neurodegenerative diseases like Alzheimer’s and Parkinson’s Disease. This new model crosses a humanized APOE mouse model with a humanized APP gene, both common implicated genetic factors in Alzheimer’s Disease. The technology also developed a Parkinson’s Disease specific...
Published: 6/25/2024
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Inventor(s): Roberta Brinton, Jean Paul Wiegand, Lisa Campbell
Keywords(s):
Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Healthcare Portfolios > Neurology
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Novel Mouse Strain for Inflammation and Neurodegeneration
This invention is a transgenic mouse model for the study of multiple sclerosis and rheumatoid arthritis. This new model crosses an HLA transgenic strain with a humanized apolipoprotein E (APOE) mouse model to create a useful tool for studying a wide array of neurodegenerative diseases, specifically the role of T-cell mediated inflammation. This new...
Published: 6/25/2024
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Inventor(s): Roberta Brinton, Kathleen Rodgers, Jean Paul Wiegand, Lisa Campbell
Keywords(s):
Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation
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Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023
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Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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All-Fiber Multicore Fiber Laser Devices
Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...
Published: 4/3/2023
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Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Fiber Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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