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Novel Mechanism Anti-Fungal with High Specificity
University of Arizona researchers have discovered a novel approach for treating fungal or yeast infections using a previously unstudied GPCR-like protein, which is integral to the regulation of cell growth in yeast cells. This protein and metabolic pathway is absent in higher-order animals, which provides a novel pathway for drugs to stop the growth...
Published: 3/12/2024
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Inventor(s): Andrew Capaldi, Ryan Wallace, Eric Lu
Keywords(s):
Category(s): Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Protein, Technology Classifications > Veterinary Medicine > Therapeutics & Vaccines, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
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Control of Microbial Growth via Novel Regulatory Events in the TORC Pathway
This invention relates to systems, methods, and compositions for treating or preventing diseases associated with eukaryotic organisms, more particularly to methods and compositions for directly or indirectly triggering and/or permitting, or inhibiting Raptor/Kog1 aggregation in specific eukaryotes. This technology is a proposed class of novel drugs...
Published: 3/12/2024
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Inventor(s): Andrew Capaldi
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biomarkers
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Control of Microbe Growth via Novel Regulatory Events in the TORC Pathway
This technology is a proposed class of novel drugs for the treatment of diseases caused by eukaryotic organisms, and a method of screening for such drugs. These antifungal and antiparasitic drugs will rely on a newly discovered cell signaling pathway that is present in many eukaryotes that cause infection in humans, but is not present in human cells....
Published: 3/12/2024
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Inventor(s): Andrew Capaldi, James Hughes Hallett
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics
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