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Phenyllactic Acid: Antimicrobial Activity against Vaginal Microbiota and Cytotoxic Properties on Human Cervical Epithelial Cells
Researchers at the University of Arizona investigated the antimicrobial properties of Phenyllactic Acid (PLA) derivatives against both commensal and Bacterial vaginosis (BV)-associated bacteria, as well as their cytotoxic effects on human cervical epithelial cells. PLA is a broad-spectrum antimicrobial compound produced by vaginal Lactobacillus species;...
Published: 11/6/2024
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Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski, Abhijit Date, Phoebe Crossley, Yogesh Sutar
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Infectious Diseases
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Novel Modalities for the Treatment of Cryptococcal Meningitis
This invention is the repurposing of oxfendazole, an FDA-approved veterinary anthelmintic benzimidazole and its novel oral bioavailability enhancing formulations for the oral treatment of cryptococcal meningitis. The oxfendazole ionic liquid containing nano formulations can lead to the development of low-cost oral treatment for cryptococcal meningitis.
Background:...
Published: 6/21/2024
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Inventor(s): Abhijit Date, Yogesh Sutar, Kirsten Nielsen, Sophie Fulton
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Drug Delivery
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Biocompatible Ionic Liquids for Improving Delivery of Therapeutic Agents
This invention relates to three types of ionic liquids (ILs) that will improve the delivery of a diverse array of therapeutic agents. The first type of ILs consists of a drug as either cation or anion and a biocompatible counterion to improve the aqueous or lipid solubility and permeability of drugs and to facilitate the incorporation of these ILs into...
Published: 9/18/2024
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Inventor(s): Abhijit Date, Yogesh Sutar, Joseph Adams
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics
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