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Search Results - niloufar+mollasalehi

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Allosteric Modulators of TDP-43 for Treating Neurodegenerative Diseases

This invention is a small molecule drug, nTRD22, that can be used to treat currently incurable neurodegenerative diseases like Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), and potentially even Alzheimer’s disease (AD) and Parkinson’s disease (PD). This molecule targets the N-terminal domain (NTD) of the DNA binding...

Published: 4/3/2023 | Inventor(s): May Khanna, Liberty Francois-Moutal, Niloufar Mollasalehi, Vijay Gokhale, David Scott, Judith Tello Vega, Haley Williams

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Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences

Development of Aptamers Neutralizing Antibodies for Demyelinating Diseases

This innovation is research involving the development of aptamers that work to neutralize antibodies which harm the myelin sheath of nerves. The innovation can be a successful treatment for both multiple sclerosis (MS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIPD). These aptamers will be very specific to block certain autoantibodies...

Published: 4/3/2023 | Inventor(s): May Khanna, Kathleen Rodgers, Maira Soto, Niloufar Mollasalehi

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Small Molecules