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Allosteric Modulators of TDP-43 for Treating Neurodegenerative Diseases
This invention is a small molecule drug, nTRD22, that can be used to treat currently incurable neurodegenerative diseases like Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), and potentially even Alzheimer’s disease (AD) and Parkinson’s disease (PD). This molecule targets the N-terminal domain (NTD) of the DNA binding...
Published: 4/3/2023   |   Inventor(s): May Khanna, Liberty Francois-Moutal, Niloufar Mollasalehi, Vijay Gokhale, David Scott, Judith Tello Vega, Haley Williams
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Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences