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Transcription Inhibition Targeted Therapy, Including for Ewing's Sarcoma
This technology features the use of a transcription inhibitor combined with a DNA damaging agent to induce tumor cell death for tumors that have FET-fused oncogenes, such as cells and tumors associated with Ewing's sarcoma and fibromyxoid Iposarcoma. This combination therapy targets members of the FET protein family that are translocated to form...
Published: 3/12/2024
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Inventor(s): Matthew Rollins, Jacob Schwartz
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics
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FET-Protein Fusions as a Marker of Sensitivity to Transcription Inhibitors and Cyclin-Dependent Kinase Inhibitors
This technology seeks to take advantage of members of the FET protein family that are translocated to form fusion oncogenes. This presents an opportunity to use FET-protein fusions as a means of identifying and treating cancer. Combined treatment of Ewing's sarcoma with a transcription inhibitor, such as flavopiridol, increases cellular sensitivity...
Published: 3/12/2024
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Inventor(s): Matthew Rollins, Jacob Schwartz, Nasiha Ahmed
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology
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Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023
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Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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All-Fiber Multicore Fiber Laser Devices
Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...
Published: 4/3/2023
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Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Fiber Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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