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Biomarker Signatures of Platelet Activation

This invention is a mechanical biomarker signature of shear effects on cells for the purpose of detecting thrombosis early so it can be treated or intercepted prior to a thrombotic event. Background: Thrombosis is a pathophysiological event that can trigger conditions like stroke or heart attack. The efficacy of many antithrombotic agents is shear...

Published: 2/9/2024 | Inventor(s): Marvin Slepian, Yana Roka Moiia, Danny Bluestein, Naing Bajaj, Michael Dicaro, Louise Hecker

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Healthcare Portfolios > Oncology

Reactive Oxygen Species Gene Signature Predicts Survival in Sepsis

This technology is a 21-gene reactive oxygen species (ROS)-associated molecular signature that predicts survival in septic patients. This particular signature has outperformed randomly generated signatures of the same signature gene size. This signature is easily assayed from peripheral blood and can potentially predict. Background: There is a significant...

Published: 11/16/2023 | Inventor(s): Louise Hecker, Marvin Slepian, Christian Bime, Tong Zhou, Nima Pouladi, Ting Wang

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Diagnostics